1: aq. KOH / ethane-1,2-diol / 48 h / Heating 2: (decarboxylation) 3: LiAlH4 / diethyl ether 4: Py / 0.5 h / 0 °C View Scheme

1: aq. KOH / ethane-1,2-diol / 48 h / Heating 2: (decarboxylation) 3: LiAlH4 / diethyl ether 4: Py / 0.5 h / 0 °C 5: (i) NaH, DMF, (ii) /BRN= 3102339/ 6: aq. KOH / ethane-1,2-diol / 48 h / Heating 7: Cu / 1 h / 170 - 180 °C / 20 Torr View Scheme

1: aq. KOH / ethane-1,2-diol / 48 h / Heating 2: (decarboxylation) View Scheme

1: aq. KOH / ethane-1,2-diol / 48 h / Heating 2: (decarboxylation) 3: LiAlH4 / diethyl ether View Scheme

1: aq. KOH / ethane-1,2-diol / 48 h / Heating 2: (decarboxylation) 3: LiAlH4 / diethyl ether 4: Py / 0.5 h / 0 °C 5: (i) NaH, DMF, (ii) /BRN= 3102339/ 6: aq. KOH / ethane-1,2-diol / 48 h / Heating View Scheme

potassium hydroxide in ethylene glycol 48 h; Heating;