2-[(1,3-二甲基-1H-吡唑-5-基)氨基]苯甲酸合成路线 (共 4 条)
反应条件
1: With sodium hydrogencarbonate in water T=20°C; 6 h; 2: With hydrogenchloride in water pH=10;
参考文献
CYTOVIA, INC.
Patent: WO2006/41900 A2, 2006 ;
Location in patent: Page/Page column 36 ;
WO 2006/041900 A2
反应条件
potassium carbonate; Cu(OAc)2 in hexane; N,N-dimethyl-formamide
参考文献
Cell Pathways, Inc.
Patent: US5852035 A1, 1998 ;
反应条件
Cu(OAc)2 in hexane; chloroform; N,N-dimethyl-formamide
参考文献
Sterling Winthrop Inc.
Patent: US5614530 A1, 1997 ;
反应条件
potassium carbonate; copper(I) bromide in N,N-dimethyl-formamide T=150°C; 1 h;
参考文献
Smith, Adrian L.; Thomson, Christopher G.; Leeson, Paul D.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 13 p. 1483 - 1486