2-氨基-6-氟苯并噻唑合成路线 （共 28 条）
反应条件
bromine; acetic acid
参考文献
Thaker; Chothani; Patel; Dhimmar; Solanki; Patel, Neeraj; Makawana
Molecular Crystals and Liquid Crystals, 2013 , vol. 575, # 1 p. 64 - 76
反应条件
1: in acetic acid T=0°C; 2: With bromine in acetic acid T=20°C; 1 h;
参考文献
Charris, Jaime; Monasterios, Melina; Dominguez, Josee; Infante, Wilson; Castro, Norma De
Heterocyclic Communications, 2002 , vol. 8, # 3 p. 275 - 280
反应条件
bromine in acetic acid T=10°C; 0.5 h;
参考文献
Lin; Kasina
Journal of Heterocyclic Chemistry, 1981 , vol. 18, # 4 p. 759 - 761
反应条件
bromine in chloroform 2 h;
参考文献
Jacquot, Yves; Cleeren, Anny; Laios, Ioanna; Ma, Yan; Boulahdour, Athem; Bermont, Laurent; Refouvelet, Bernard; Adessi, Gerard; Leclercq, Guy; Xicluna, Alain
Biological and Pharmaceutical Bulletin, 2002 , vol. 25, # 3 p. 335 - 341
反应条件
1: aqueous hydrochloric acid 2: bromine; SO2Cl2; chlorobenzene View Scheme
反应条件
1: hydrochloric acid / H2O / 4 h / Heating 2: bromine / CHCl3 / 4 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 16 p. 5678 - 5682
反应条件
bromine in acetic acid
参考文献
Die Pharmazie, , vol. 22, # 6 p. 229 - 233
反应条件
1: ethanol; ammonia 2: bromine; CHCl3 View Scheme
参考文献
Journal of the Indian Chemical Society, , vol. 8, p. 147,163
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 27, # 1-12 p. 189 - 190
反应条件
tert.-butylnitrite; copper dichloride in acetonitrile T=65°C; 2 h;
参考文献
AMGEN INC.; Allen, Jennifer R.; Amegadzie, Albert; Andrews, Kristin L.; Brown, James; Chen, Jian J.; Chen, Ning; Harrington, Essa Hu; Liu, Qingyian; Nguyen, Thomas T.; Pickrell, Alexander J.; Qian, Wenyuan; Rumfelt, Shannon; Rzasa, Robert M.; Yuan, Chester Chenguang; Zhong, Wenge
Patent: US2013/225552 A1, 2013 ;
Location in patent: Paragraph 0976 ;
