1-(2-吡啶基)哌嗪合成路线

参考文献

NOVO NORDISK A/S
Patent: WO2004/111007 A1, 2004 ;
Location in patent: Page 62 ;
WO 2004/111007 A1

34803-66-21-(2-吡啶基)哌嗪

87394-54-51-(6-氯吡啶-2-基)哌嗪

参考文献

Louerat, Frederic; Gros, Philippe; Fort, Yves
Tetrahedron, 2005 , vol. 61, # 20 p. 4761 - 4768

34803-66-21-(2-吡啶基)哌嗪+

104373-99-1

104373-77-5

参考文献

Catto, Alberto; Motta, Gianni; Tajana, Alberto; Cazzulani, Pietro; Nardi, Dante; Leonardi, Amedeo
Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 13 - 19

34803-66-21-(2-吡啶基)哌嗪+

79-10-7丙烯酸

104373-85-53-(4-吡啶-2-哌嗪-1-基)-丙酸

参考文献

Catto, Alberto; Motta, Gianni; Tajana, Alberto; Cazzulani, Pietro; Nardi, Dante; Leonardi, Amedeo
Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 13 - 19

34803-66-21-(2-吡啶基)哌嗪+

103-63-9(2-溴乙基)苯

1033-69-8

参考文献

Komoto; Okada; Sato; Niino; Oka; Sakamoto
Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 10 p. 1314 - 1320

34803-66-21-(2-吡啶基)哌嗪

1033-69-8

参考文献

Maeda, Dean Y.; Williams, Wanda; Kim, Wes E.; Thatcher, Linn N.; Bowen, Wayne D.; Coop, Andrew
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 3 p. 497 - 500

34803-66-21-(2-吡啶基)哌嗪+

21076-11-94-(4-甲基苯基)-3-氨基硫脲

87555-65-5+

100-61-8N-甲基苯胺

参考文献

Shakya, Bhushan; Yadav, Paras Nath; Ueda, Jun-Ya; Awale, Suresh
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 2 p. 458 - 461

34803-66-21-(2-吡啶基)哌嗪+

3874-54-24-氯-4'-氟苯丁酮

1649-18-9阿扎哌隆

参考文献

Jaen; Caprathe; Pugsley; Wise; Akunne
Journal of Medicinal Chemistry, 1993 , vol. 36, # 24 p. 3929 - 3936

34803-66-21-(2-吡啶基)哌嗪

220941-93-55-氟-2-{[4-(2-吡啶)-1-哌嗪]甲基}-1H-吲哚

参考文献

Cowart, Marlon; Latshaw, Steven P.; Bhatia, Pramila; Daanen, Jerome F.; Rohde, Jeffrey; Nelson, Sherry L.; Patel, Meena; Kolasa, Teodozyi; Nakane, Masaki; Uchic, Marie E.; Miller, Loan N.; Terranova, Marc A.; Chang, Renjie; Donnelly-Roberts, Diana L.; Namovic, Marian T.; Hollingsworth, Peter R.; Martino, Brenda R.; Lynch III, James J.; Sullivan, James P.; Hsieh, Gin C.; Moreland, Robert B.; Brioni, Jorge D.; Stewart, Andrew O.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 15 p. 3853 - 3864

34803-66-21-(2-吡啶基)哌嗪

120182-07-2

参考文献

Bosc; Jarry; Carpy; Panconi; Descas
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 5 p. 437 - 442