3-溴-4-甲氧基苯甲醛合成路线 （共 37 条）
反应条件
dicobalt octacarbonyl; potassium carbonate; methyloxirane in methanol T=60°C; P=760 Torr; 9 h;
参考文献
Boyarskii; Zhesko; Lanina
Russian Journal of Applied Chemistry, 2005 , vol. 78, # 11 p. 1844 - 1848
反应条件
1: aqueous NaOH / 50 °C 2: benzene; HCl / 0 °C 3: ethanol View Scheme
参考文献
Gibson,M.S. et al.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 2234 - 2238
反应条件
1: aqueous NaOH / 50 °C 2: benzene; HCl / 0 °C 3: ethanol 4: aq.-ethanolic NaOH-solution View Scheme
参考文献
Gibson,M.S. et al.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 2234 - 2238
反应条件
1: 97 percent / toluene-4-sulfonic acid / toluene / 24 h / Heating 2: 1.) 2.5 M nBuLi; 2.) tributyl borate; 3.) 2M HCl / 1.) diethyl ether, hexane, -70 deg C, 4 h; 2.) 12 h, 20 deg C; 3.) water View Scheme
参考文献
European Journal of Organic Chemistry, , # 5 p. 877 - 888
反应条件
hydroxylamine hydrochloride; 1-propanephosphonic acid cyclic anhydride; triethylamine in ethyl acetate; N,N-dimethyl-formamide T=100°C;
参考文献
Augustine, John Kallikat; Atta, Rajendra Nath; Ramappa, Balakrishna Kolathur; Boodappa, Chandrakantha
Synlett, 2009 , # 20 p. 3378 - 3382
反应条件
n-butyllithium in tetrahydrofuran T=0°C;
参考文献
Caijo, Frederic; Tripoteau, Fabien; Bellec, Aurelien; Crevisy, Christophe; Basle, Olivier; Mauduit, Marc; Briel, Oliver
Catalysis Science and Technology, 2013 , vol. 3, # 2 p. 429 - 435
反应条件
n-butyllithium in tetrahydrofuran T=0 - 20°C; 1 h;
参考文献
Lawrence, Nicholas; Bushell, Simon
Tetrahedron Letters, 2001 , vol. 42, # 43 p. 7671 - 7674
反应条件
boron tribromide in dichloromethane T=0 - 20°C; 5 h;
参考文献
ViroPharma Incorporated
Patent: US6495580 B1, 2002 ;
反应条件
1: With 3-chloro-benzenecarboperoxoic acid in dichloromethane T=40°C; 72 h; 2: With sodium methylate in ethanol T=20°C; 1 h;
参考文献
Moreno-Sanz, Guillermo; Duranti, Andrea; Melzig, Laurin; Fiorelli, Claudio; Ruda, Gian Filippo; Colombano, Giampiero; Mestichelli, Paola; Sanchini, Silvano; Tontini, Andrea; Mor, Marco; Bandiera, Tiziano; Scarpelli, Rita; Tarzia, Giorgio; Piomelli, Daniele
Journal of Medicinal Chemistry, 2013 , vol. 56, # 14 p. 5917 - 5930
反应条件
in water; ethylene glycol; toluene
参考文献
Sanofi-Synthelabo
Patent: US6673790 B1, 2004 ;
US 6673790 B1
