4,4,4-三氟-1-苯基-3-(三氟甲基)-1,3-丁二醇合成路线 (共 2 条)
反应条件
hydrogen; palladium on activated charcoal in di-isopropyl ether T=40°C; P=7500.75 Torr; 12 h;
参考文献
Komata, Takeo; Matsunaga, Kei; Hirotsu, Yoshiki; Akiba, Shinya; Ogura, Katsuyuki
Journal of Fluorine Chemistry, 2007 , vol. 128, # 8 p. 902 - 909
反应条件
1: 1,1-bis(trifluoromethyl)-2-bromoethanol With n-butyllithium in diethyl ether; hexane T=-78°C; 2: benzaldehyde in diethyl ether; hexane T=-78 - -10°C; 2 h;
参考文献
Grushin, Vladimir V.; Marshall, William J.; Halliday, Gary A.; Davidson, Fredric; Petrov, Viacheslav A.
Journal of Fluorine Chemistry, 2002 , vol. 117, # 2 p. 121 - 129