(S)-(-)-2-甲基-1-苯基-1-丙醇合成路线 （共 40 条）
反应条件
toluene-4-sulfonic acid in methanol 3 h;
参考文献
Noe, Christian R.
Chemische Berichte, 1982 , vol. 115, # 4 p. 1591 - 1606
反应条件
diethylzinc; planar-chiral ferrocenyl oxazoline 3 in toluene T=10°C; Title compound not separated from byproducts;
参考文献
Angewandte Chemie (International Edition in English), , vol. 39, # 19 p. X3465-3467
反应条件
1: 1-hydroxy-2-(1-methyl)-propylbenzene With iPr2NCHEt2; (-)-Tetramisole in tetrahydrofuran T=-78°C; 0.5 h; Molecular sieveInert atmosphereResolution of racemate; 2: triphenyl-silyl chloride in tetrahydrofuran T=-78°C; 48 h; Inert atmosphereResolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Organic Letters, , vol. 13, # 15 p. 3794 - 3797
反应条件
1: triphenyl boroxine With diethylzinc in toluene T=60°C; 4 h; 2: isobutyraldehyde With (S)-dendritic pyrrolidinylmethanol C116H105NO15 in toluene T=-15°C; 6 h; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 70, # 18 p. 7432 - 7435
反应条件
dilithium salt of (2S,5S)-2, 5-diisopropylpiperazine 1) toluene, hexane, RT, 30 min, 2) RT, 20h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2717 - 2720
反应条件
tertiary amine-based nucleophilic catalyst in 1,1-dimethylpropan-1-ol T=0°C; 17 h;
参考文献
Chemistry Letters, , # 11 p. 1114 - 1115
反应条件
(R)-7-chloro-2-phenyl-2,3-dihydroimidazo[1,2-a]quinoline; N-ethyl-N,N-diisopropylamine in chloroform T=0°C; 8 h; Product distribution; Further Variations:Reagents;
参考文献
Organic Letters, , vol. 7, # 16 p. 3445 - 3447
反应条件
(5aS,10aS)-(-)-Octahydro-5H,10H-dipyrrololt;1,2-a:1',2'-dgt;pyrazin in tetrahydrofuran; toluene T=-100°C; 5 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Chemische Berichte, , vol. 127, # 7 p. 1323 - 1326
反应条件
tetra-n-butylammonium tetrafluoroborate; (1R,2S)-(-)-N,N-dimethylephedrinium tetrafluoroborate in water; N,N-dimethyl-formamide Electrolysis;
参考文献
Yadav, Ashok K.; Singh, Arpita
Bulletin of the Chemical Society of Japan, 2002 , vol. 75, # 3 p. 587 - 588
反应条件
benzoic acid anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Title compound not separated from byproducts.;
参考文献
Tetrahedron Letters, , vol. 48, # 47 p. 8314 - 8317
