2-(5-甲氧基-1H-吲哚-3-基)-1-甲苯磺酰-1H-吡咯并[2,3-b]吡啶合成路线 （共 6 条）
反应条件
sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) in DMF (N,N-dimethyl-formamide); water T=20°C; 4 h; Heating / reflux;
参考文献
Nemecek, Conception; Metz, William A.; Wentzler, Sylvie; Ding, Fa-Xiang; Venot, Corinne; Souaille, Catherine; Dagallier, Anne; Maignan, Sebastien; Guilloteau, Jean-Pierre; Bernard, Francois; Henry, Alain; Grapinet, Sandrine; Lesuisse, Dominique
Chemical Biology and Drug Design, 2010 , vol. 76, # 2 p. 100 - 106
反应条件
1: n-butyllithium; iodine / tetrahydrofuran 2: tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 110 °C View Scheme
参考文献
Nemecek, Conception; Metz, William A.; Wentzler, Sylvie; Ding, Fa-Xiang; Venot, Corinne; Souaille, Catherine; Dagallier, Anne; Maignan, Sebastien; Guilloteau, Jean-Pierre; Bernard, Francois; Henry, Alain; Grapinet, Sandrine; Lesuisse, Dominique
Chemical Biology and Drug Design, 2010 , vol. 76, # 2 p. 100 - 106
反应条件
1: tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide / water; toluene 2: n-butyllithium; iodine / tetrahydrofuran 3: tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 110 °C View Scheme
参考文献
Nemecek, Conception; Metz, William A.; Wentzler, Sylvie; Ding, Fa-Xiang; Venot, Corinne; Souaille, Catherine; Dagallier, Anne; Maignan, Sebastien; Guilloteau, Jean-Pierre; Bernard, Francois; Henry, Alain; Grapinet, Sandrine; Lesuisse, Dominique
Chemical Biology and Drug Design, 2010 , vol. 76, # 2 p. 100 - 106
反应条件
1: 4-(N,N-dimethlyamino)pyridine; iodine; potassium hydroxide / N,N-dimethyl-formamide 2: n-butyllithium; boric acid trimethyl ester 3: tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 110 °C View Scheme
参考文献
Nemecek, Conception; Metz, William A.; Wentzler, Sylvie; Ding, Fa-Xiang; Venot, Corinne; Souaille, Catherine; Dagallier, Anne; Maignan, Sebastien; Guilloteau, Jean-Pierre; Bernard, Francois; Henry, Alain; Grapinet, Sandrine; Lesuisse, Dominique
Chemical Biology and Drug Design, 2010 , vol. 76, # 2 p. 100 - 106
反应条件
1: tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide / water; toluene 2: n-butyllithium; iodine / tetrahydrofuran 3: tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 110 °C View Scheme
参考文献
Nemecek, Conception; Metz, William A.; Wentzler, Sylvie; Ding, Fa-Xiang; Venot, Corinne; Souaille, Catherine; Dagallier, Anne; Maignan, Sebastien; Guilloteau, Jean-Pierre; Bernard, Francois; Henry, Alain; Grapinet, Sandrine; Lesuisse, Dominique
Chemical Biology and Drug Design, 2010 , vol. 76, # 2 p. 100 - 106
反应条件
1: n-butyllithium; boric acid trimethyl ester 2: tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 110 °C View Scheme
参考文献
Nemecek, Conception; Metz, William A.; Wentzler, Sylvie; Ding, Fa-Xiang; Venot, Corinne; Souaille, Catherine; Dagallier, Anne; Maignan, Sebastien; Guilloteau, Jean-Pierre; Bernard, Francois; Henry, Alain; Grapinet, Sandrine; Lesuisse, Dominique
Chemical Biology and Drug Design, 2010 , vol. 76, # 2 p. 100 - 106
