1-[(4-甲基苯基)磺酰基]-1H-吡咯并[2,3-b]吡啶-4-甲腈合成路线 （共 2 条）
反应条件
1: With zinc in N,N-dimethyl acetamide T=20°C; 0.75 h; 2: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in N,N-dimethyl acetamide T=140°C; 1.5 h;
参考文献
Aventis Pharma S.A.
Patent: US2007/93480 A1, 2007 ;
Location in patent: Page/Page column 67-68 ;
反应条件
1: 1-(2,6-dimethyl-1,4-dihydropyridin-4-one)-1H-pyrrolo[2,3-b]pyridinium tetrafluoroborate; potassium cyanide in water T=20°C; 48 h; 2: p-toluenesulfonyl chloride With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in water; toluene T=20°C; 72 h;
参考文献
Cox, Paul J.; Majid, Tahir N.; Lai, Justine Y.Q.; Morley, Andrew D.; Amendola, Shelley; Deprets, Stephanie D.; Edlin, Christopher
Patent: US2004/9983 A1, 2004 ;
Location in patent: Page/Page column 119 ;
