N1-[4-(三氟甲基0苯基]乙酰氨合成路线 （共 34 条）
反应条件
hydrogen; palladium on activated charcoal
参考文献
Debarge, Sebastien; Violeau, Bruno; Bendaoud, Nohair; Jacquesy, Jean-Claude
Tetrahedron Letters, 2003 , vol. 44, # 9 p. 1747 - 1750
反应条件
[Ru(tris(2,2'-bipyridyl))3]Cl2·6H2O; anhydrous copper acetate; potassium carbonate in N,N-dimethyl-formamide T=60°C; 12 h; Inert atmosphere26 W fluorescent light bulbs;
参考文献
Ye, Yingda; Sanford, Melanie S.
Journal of the American Chemical Society, 2012 , vol. 134, # 22 p. 9034 - 9037
反应条件
1: With hydrogen fluoride; SbF5 T=-20 - 0°C; 0.5 h; 2: With pyridine; hydrogen fluoride T=-78 - 0°C;
参考文献
Debarge, Sebastien; Violeau, Bruno; Bendaoud, Nohair; Jacquesy, Jean-Claude
Tetrahedron Letters, 2003 , vol. 44, # 9 p. 1747 - 1750
反应条件
1: tin; aqueous hydrochloric acid / unter Zusatz von Essigsaeure View Scheme
参考文献
Helvetica Chimica Acta, , vol. 30, p. 107,110
反应条件
1: copper / dimethyl sulfoxide / 12 h / 60 °C / |Inert atmosphere 2: potassium carbonate / methanol; water / 2 h / 20 °C / |Inert atmosphere 3: 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate); silver nitrate / water; acetone / 1 h / 55 °C / |Inert atmosphere; |Schlenk technique View Scheme
参考文献
Organic Letters, , vol. 15, # 11 p. 2648 - 2651
反应条件
1: potassium carbonate / methanol; water / 2 h / 20 °C / |Inert atmosphere 2: 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate); silver nitrate / water; acetone / 1 h / 55 °C / |Inert atmosphere; |Schlenk technique View Scheme
参考文献
Organic Letters, , vol. 15, # 11 p. 2648 - 2651
反应条件
1: SbF3 / 100 °C 2: tin (II)-chloride; aq.-ethanolic hydrochloric acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 69, p. 2352
反应条件
1: aqueous NaOBr solution 2: SbF3 / 100 °C 3: tin (II)-chloride; aq.-ethanolic hydrochloric acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 69, p. 2352
反应条件
1: (trifluoromethyl)-trimethylsilane With copper(I) isothiocyanate; caesium carbonate in acetonitrile T=20°C; 0.166667 h; Inert atmosphere; 2: 4-acetamidobenzenediazonium tetrafluoroborate in acetonitrile T=20°C; Sandmeyer Reaction; 16 h; Inert atmosphere;
参考文献
Danoun, Gregory; Bayarmagnai, Bilguun; Gruenberg, Matthias F.; Goossen, Lukas J.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 31 p. 7972 - 7975
Angew. Chem., 2013 , vol. 125, # 31 p. 8130 - 8133
反应条件
1.1: HF; SbF5 / 2 h / -20 - 0 °C 1.2: 84 percent / HF; pyridine / -78 - 0 °C 2.1: 95 percent / H2 / Pd/C View Scheme
参考文献
Tetrahedron Letters, , vol. 44, # 9 p. 1747 - 1750
