N-甲基-2-(3,4-二甲氧基苯基)乙胺合成路线 （共 52 条）
反应条件
1: With hydrogen; 5-palladium/activated carbon in water T=75°C; P=2585.81 Torr; 16 - 40 h; 2: With sodium hydroxide in water; toluene pH=12; Product distribution / selectivity;
参考文献
ALBANI, Davide; Arosio, Roberto; Merli, Valeriano
Patent: US2009/171110 A1, 2009 ;
Location in patent: Page/Page column 6 ;
反应条件
1: chloral 2: LiAlH4; THF View Scheme
参考文献
Journal of Scientific and Industrial Research, , vol. 17B, p. 219,223
反应条件
sodium tetrahydroborate; boron trifluoride diethyl etherate in tetrahydrofuran 1) room temperature, 1 h; 2) reflux, 3 h;
参考文献
Sindelar, Karel; Dobrovsky, Karel; Krejci, Ivan; Polivka, Zdenek
Collection of Czechoslovak Chemical Communications, 1995 , vol. 60, # 5 p. 894 - 902
反应条件
sodium hydroxide in methanol; dichloromethane
反应条件
sodium hydride in tetrahydrofuran 4 h; Ambient temperature;
参考文献
Theodore; Nelson
Journal of Organic Chemistry, 1987 , vol. 52, # 7 p. 1309 - 1315
反应条件
1: 1,2-dimethoxy-4-ethenyl-benzene With Schwartz's reagent in tetrahydrofuran T=25°C; 2: N-methylhydroxylamine-O-sulphonic acid in tetrahydrofuran T=50°C; 0.5 h;
参考文献
Strom, Alexandra E.; Hartwig, John F.
Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8909 - 8914
反应条件
hydrogenchloride in tetrahydrofuran 2 h; Ambient temperature; Yield given;
参考文献
Journal of the American Chemical Society, , vol. 104, # 3 p. 877 - 879
反应条件
1: sodium borohydride, 10percent HCl / aq. ethanol / 1 h / 0 °C / pH ca.6 2: 10percent HCl / tetrahydrofuran / 2 h / Ambient temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 104, # 3 p. 877 - 879
反应条件
in benzyl-methyl-amine
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 6 h; Inert atmosphereReflux;
参考文献
Crestey, Francois; Jensen, Anders A.; Borch, Morten; Andreasen, Jesper Tobias; Andersen, Jacob; Balle, Thomas; Kristensen, Jesper Langgaard
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9673 - 9682
