N-甲基-2-(3,4-二甲氧基苯基)乙胺合成路线 （共 52 条）
反应条件
formic acid in isopropyl alcohol; toluene
参考文献
BASF Aktiengesellschaft
Patent: US4350636 A1, 1982 ;
反应条件
triethylamine in toluene 24 h; Heating;
参考文献
Gubin, Jean; Lucchetti, Jean; Mahaux, Jean; Nisato, Dino; Rosseels, Gilbert; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 981 - 988
参考文献
Brenna, Elisabetta; Fuganti, Claudio; Grasselli, Piero; Serra, Stefano
European Journal of Organic Chemistry, 2001 , # 7 p. 1349 - 1357
反应条件
triethylamine in tetrahydrofuran
T=80°C; 48 h; Yield given;
参考文献
Theodore; Nelson
Journal of Organic Chemistry, 1987 , vol. 52, # 7 p. 1309 - 1315
反应条件
1: water / und Erwaermen des Reaktionsprodukts mit konz. Salzsaeure
2: water; hydriodic acid
View Scheme
参考文献
Buck
Journal of the American Chemical Society, 1934 , vol. 56, p. 1769
反应条件
triethylamine in tetrahydrofuran
T=80°C; 48 h; Yield given;
参考文献
Theodore; Nelson
Journal of Organic Chemistry, 1987 , vol. 52, # 7 p. 1309 - 1315
反应条件
sodium hydroxide; Adam's catalyst in methanol; water
参考文献
Spofa, spojene podniky pro zdravotnickou
Patent: US4847403 A1, 1989 ;
反应条件
in acetic acid; trifluoroacetic acid
Pictet-Spengler reaction; 0.5 h; Heating;
参考文献
Ivanov, Iliyan; Venkov, Atanas
Heterocycles, 2001 , vol. 55, # 8 p. 1569 - 1580
反应条件
water
und Erwaermen des Reaktionsprodukts mit konz. Salzsaeure;
参考文献
Buck
Journal of the American Chemical Society, 1934 , vol. 56, p. 1769
反应条件
potassium iodide in N,N-dimethyl-formamide
12 h; Inert atmosphereReflux;
参考文献
Lorion, Magali; Couture, Axel; Deniau, Eric; Grandclaudon, Pierre
Synthesis, 2009 , # 11 art. no. Z01309SS, p. 1897 - 1903
