2-(4-溴苯基)-1-吗啉代乙酮合成路线 （共 4 条）
反应条件
in dichloromethane T=0 - 5°C; 1 h;
参考文献
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY; AUCKLAND UNISERVICES LIMITED; RUGA CORPORATION; GIACCA, Amato; LAI, Edwin; RAZORENOVA, Olga; CHAN, Denise; HAY, Michael, Patrick; BONNET, Muriel; SUN, Connie; TABIBIAZAR, Ray; YUEN, Po-wai
Patent: WO2013/155338 A2, 2013 ;
Location in patent: Page/Page column 171 ;
反应条件
1: 2-(4-bromophenyl)acetic acid With oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane 2: morpholine in dichloromethane T=0°C; 1 h;
参考文献
Chiba, Shunsuke; Zhang, Line; Sanjaya, Stephen; Ang, Gim Yean
Tetrahedron, 2010 , vol. 66, # 30 p. 5692 - 5700
反应条件
1: thionyl chloride / 2 h / |Reflux 2: dichloromethane / 1 h / 0 - 5 °C View Scheme
参考文献
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY; AUCKLAND UNISERVICES LIMITED; RUGA CORPORATION; GIACCA, Amato; LAI, Edwin; RAZORENOVA, Olga; CHAN, Denise; HAY, Michael, Patrick; BONNET, Muriel; SUN, Connie; TABIBIAZAR, Ray; YUEN, Po-wai
Patent: WO2013/155338 A2, 2013 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=-30 - 20°C; 2.5 h; Inert atmosphere;
参考文献
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY; AUCKLAND UNISERVICES LIMITED; RUGA CORPORATION; GIACCA, Amato; LAI, Edwin; RAZORENOVA, Olga; CHAN, Denise; HAY, Michael, Patrick; BONNET, Muriel; SUN, Connie; TABIBIAZAR, Ray; YUEN, Po-wai
Patent: WO2013/155338 A2, 2013 ;
Location in patent: Page/Page column 171-172 ;
