1-氯异喹啉-3-羧酸甲酯合成路线 （共 8 条）
反应条件
trichlorophosphate in methanol T=130°C; 0.166667 h; Microwave irradiation;
参考文献
Saari, Raimo; Toermae, Jonna-Carita; Nevalainen, Tapio
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 2 p. 939 - 950
反应条件
1: 93 percent / H2SO4 / 8 h / Heating 2: 72 percent / 10percent Pd/C / diphenyl ether / Heating 3: 85 percent / POCl3; K2CO3 / acetonitrile / 1.5 h / Heating View Scheme
参考文献
Janin, Yves L.; Roulland, Emmanuel; Beurdeley-Thomas, Arnaud; Decaudin, Didier; Monneret, Claude; Poupon, Marie-France
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 4 p. 529 - 532
反应条件
1: 72 percent / 10percent Pd/C / diphenyl ether / Heating 2: 85 percent / POCl3; K2CO3 / acetonitrile / 1.5 h / Heating View Scheme
参考文献
Janin, Yves L.; Roulland, Emmanuel; Beurdeley-Thomas, Arnaud; Decaudin, Didier; Monneret, Claude; Poupon, Marie-France
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 4 p. 529 - 532
反应条件
1: 61 percent / Ac2O; NaOAc 2: 79 percent / KOH / methanol 3: 84 percent / POCl3; HCl / 1.5 h / Heating View Scheme
参考文献
Tucker, Sonia C; Brown, John M; Oakes, John; Thornthwaite, David
Tetrahedron, 2001 , vol. 57, # 13 p. 2545 - 2554
反应条件
1: 79 percent / KOH / methanol 2: 84 percent / POCl3; HCl / 1.5 h / Heating View Scheme
参考文献
Tucker, Sonia C; Brown, John M; Oakes, John; Thornthwaite, David
Tetrahedron, 2001 , vol. 57, # 13 p. 2545 - 2554
反应条件
1: K2CO3 / acetone 2: 61 percent / Ac2O; NaOAc 3: 79 percent / KOH / methanol 4: 84 percent / POCl3; HCl / 1.5 h / Heating View Scheme
参考文献
Tucker, Sonia C; Brown, John M; Oakes, John; Thornthwaite, David
Tetrahedron, 2001 , vol. 57, # 13 p. 2545 - 2554
反应条件
sodium hydroxide in ethanol 0.5 h; Reflux;
参考文献
Yuan, Yunyun; Elbegdorj, Orgil; Beletskaya, Irina O.; Selley, Dana E.; Zhang, Yan
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 18 p. 5045 - 5048
反应条件
bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide
T=130°C; 0.5 h;
参考文献
Yuan, Yunyun; Elbegdorj, Orgil; Beletskaya, Irina O.; Selley, Dana E.; Zhang, Yan
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 18 p. 5045 - 5048
