4,4,5,5-四甲基-2-(芘-1-基)-1,3,2-二噁唑环戊硼烷合成路线 （共 15 条）
反应条件
1: 1-Bromopyrene With n-butyllithium in tetrahydrofuran T=-78°C; 0.5 h; 2: 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in tetrahydrofuran 1 h;
参考文献
KIM, Kong Kyeom; Hong, Sung Kil; Jang, Hye Young; Jeong, Dong Seob
Patent: US2014/77165 A1, 2014 ;
Location in patent: Paragraph 0103-0105 ;
反应条件
triethylamine; Cl2Pd(PPh3)2 in toluene
参考文献
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; THE UNIVERSITY OF SOUTHERN CALIFORNIA
Patent: US2012/1155 A1, 2012 ;
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium acetate in 1,4-dioxane 9 h; Reflux;
参考文献
ALPHA CHEM CO., LTD.; NAM, Hyun Goog; LIM, Dae Won; KIM, Jae Yong; PARK, Sang Mi; JANG, Seung Hee; LEE, Sang Youn; HAM, Ju Seok; CHO, Kyu Oh; KIM, Hyun Don
Patent: WO2013/180376 A1, 2013 ;
Location in patent: Paragraph 223; 224; 225; 226 ;
反应条件
1: 1-Bromopyrene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: With tri-isopropoxy-borane in tetrahydrofuran; hexane T=-78 - 20°C; 0.5 h; 3: 2,3-dimethylbutane-2,3-diol in diethyl ether; hexane T=40°C; 0.75 h;
参考文献
Beinhoff, Matthias; Weigel, Wilfried; Jurczok, Martin; Rettig, Wolfgang; Modrakowski, Claudia; Bruedgam, Irene; Hartl, Hans; Schlueter, A. Dieter
European Journal of Organic Chemistry, 2001 , # 20 p. 3819 - 3829
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine in toluene Inert atmosphereReflux;
参考文献
Diev, Vyacheslav V.; Schlenker, Cody W.; Hanson, Kenneth; Zhong, Qiwen; Zimmerman, Jeramy D.; Forrest, Stephen R.; Thompson, Mark E.
Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 143 - 159
反应条件
1: pyrene With AlCl3, aluminium chloride; BCl3*C9H13N in 1,2-dichloro-benzene T=80°C; 48 h; GloveboxInert atmosphere; 2: 2,3-dimethylbutane-2,3-diol With triethylamine T=0 - 20°C; 1 h; Inert atmosphere; Overall yield = 18 mg; regioselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 135, # 1 p. 474 - 487
反应条件
1.1: hydrogen bromide / methanol; diethyl ether / 10 - 15 °C 1.2: 24 h / 20 °C 2.1: n-butyllithium / tetrahydrofuran View Scheme
参考文献
New Journal of Chemistry, , vol. 37, # 6 p. 1833 - 1842
反应条件
1: n-butyllithium / tetrahydrofuran 2: dichloromethane View Scheme
参考文献
Journal of Chemical Research, , vol. 37, # 4 p. 242 - 247
反应条件
in diethyl ether; dichloromethane T=20°C; 24 h;
参考文献
Journal of Organic Chemistry, , vol. 77, # 1 p. 143 - 159
参考文献
Journal of Chemical Research, , vol. 37, # 4 p. 242 - 247
