3,3-二甲基环丁烷甲酸合成路线 （共 18 条）
反应条件
T=200°C; Decarboxylation; 2.5 h;
参考文献
El-Hachach, Nizar; Fischbach, Matthias; Gerke, Ralf; Fitjer, Lutz
Tetrahedron, 1999 , vol. 55, # 19 p. 6119 - 6128
反应条件
potassium hydroxide in ethanol
参考文献
Brannock,K.C. et al.
Journal of Organic Chemistry, 1964 , vol. 29, p. 801 - 812
反应条件
1: (i) TsOMe, (ii) aq. KOH, EtOH 2: aq. KOH / ethanol View Scheme
参考文献
Brannock,K.C. et al.
Journal of Organic Chemistry, 1964 , vol. 29, p. 801 - 812
反应条件
1: 90 percent / potassium hydroxide / ethanol; H2O / 4 h / Heating 2: 83 percent / 2.5 h / 200 °C View Scheme
参考文献
El-Hachach, Nizar; Fischbach, Matthias; Gerke, Ralf; Fitjer, Lutz
Tetrahedron, 1999 , vol. 55, # 19 p. 6119 - 6128
反应条件
1: NaI 2: KOH 3: saponification 4: 180 °C View Scheme
参考文献
Park; Varick; Newcomb
Tetrahedron Letters, 1990 , vol. 31, # 21 p. 2975 - 2978
反应条件
2: NaI 3: KOH 4: saponification 5: 180 °C View Scheme
参考文献
Park; Varick; Newcomb
Tetrahedron Letters, 1990 , vol. 31, # 21 p. 2975 - 2978
反应条件
potassium hydroxide; ethylene glycol
参考文献
Julia; Rouault
Bulletin de la Societe Chimique de France, 1959 , p. 1833,1839
反应条件
2: sodium tert-pentylate 3: KOH; ethylene glycol View Scheme
参考文献
Julia; Rouault
Bulletin de la Societe Chimique de France, 1959 , p. 1833,1839
反应条件
1: tetrahydrofuran; lithium-<tri-tert-butoxyalanate> 3: sodium tert-pentylate 4: KOH; ethylene glycol View Scheme
参考文献
Julia; Rouault
Bulletin de la Societe Chimique de France, 1959 , p. 1833,1839
反应条件
1: sodium tert-pentylate 2: KOH; ethylene glycol View Scheme
参考文献
Julia; Rouault
Bulletin de la Societe Chimique de France, 1959 , p. 1833,1839
