1: SOCl2 / 1.67 h / Heating 2: 100 percent / Et3N, trichloroacetyl chloride / CH2Cl2 / 1 h / 0 °C 3: 35 percent / NBS / CCl4 / 4 h / Heating; Irradiation 4: 55 percent / Me3NO*2H2O, DMSO / CH2Cl2 / Ambient temperature View Scheme

1: SOCl2 / 1.67 h / Heating 2: 100 percent / Et3N, trichloroacetyl chloride / CH2Cl2 / 1 h / 0 °C 3: 35 percent / NBS / CCl4 / 4 h / Heating; Irradiation 4: 55 percent / Me3NO*2H2O, DMSO / CH2Cl2 / Ambient temperature 5: 91 percent / NH2OH*HCl, K2CO3 / methanol; H2O / 2.67 h / Heating View Scheme

1: SOCl2 / 1.67 h / Heating 2: aq. NH3 / CH2Cl2 View Scheme

1: SOCl2 / 1.67 h / Heating 2: 100 percent / Et3N, trichloroacetyl chloride / CH2Cl2 / 1 h / 0 °C View Scheme

borane-THF in tetrahydrofuran 3.5 h; Ambient temperature;

bromine; iron T=20°C; 20 h;

1: dibenzoyl peroxide; N-bromosuccinmide / tetrachloromethane / 40 h / 77 °C 2: silver nitrate / ethanol; water / 0.75 h / 50 °C View Scheme

1: oxalyl chloride, DMF / tetrahydrofuran / 0.5 h / Heating 2: sulfuryl chloride, benzoyl peroxide / benzene / 2.5 h / Heating 3: 1.) AlCl3 / 1.) CH2Cl2, RT, 10 min, 2.) CH2Cl2, RT, 2.5 h 4: 16.0 g / NaN3 / dimethylformamide / 3 h / Ambient temperature 5: 13.59 g / H2O, PPh3 / tetrahydrofuran / 16 h / Ambient temperature 6: 12.14 g / Et3N / acetonitrile / a) RT, 30 min, b) 60 deg C, 2 h 7: H2 / 5percent Pt/C / tetrahydrofuran / 18 h / 3040 Torr / Ambient temperature 8: AcOH / 2 h / Heating 9: tetrakis(triphenylphosphine)palladium(0) / toluene / 3 h / 120 °C 10: KF*H2O / dimethylformamide / a) 0 deg C, 30 min, b) RT, 1.5 h View Scheme

1: 72 percent / K2CO3 / acetone / Heating 2: NBS; AIBN / CCl4 / Heating 3: 1.94 g / AgNO3; H2O / acetone View Scheme

1.1: potassium carbonate / ethyl acetate; acetone / 175.2 h / 25 - 90 °C 2.1: 2,2'-azo-bisisobutyronitrile; N-bromosuccinmide / tetrachloromethane / 20 h / 100 °C 2.2: 24 h / Darkness View Scheme