4-氟-Alpha-甲基苯乙烯合成路线 （共 27 条）
反应条件
(i) Mg, Et2O, (ii) aq. H2SO4; Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 95, p. 6763 - 6770
反应条件
(i), (ii) TsOH; Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 101, # 26 p. 7687 - 7693
反应条件
potassium tert-butylate in tetrahydrofuran Wittig olefination;
参考文献
Chemistry - A European Journal, , vol. 13, # 33 p. 9207 - 9215
反应条件
(i), (ii) Al2O3, P2O5; Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 119 - 125
反应条件
(hydroxy(tosyloxy)iodo)benzene in methanol T=20°C; 0.333333 h;
参考文献
Justik, Michael W.; Koser, Gerald F.
Tetrahedron Letters, 2004 , vol. 45, # 32 p. 6159 - 6163
反应条件
1: 2-methyl-2-(4-fluorophenyl)-ethene With ozone in methanol T=20°C; 2: methanol With dihydrogen peroxide T=20°C;
参考文献
Irfan, Muhammad; Glasnov, Toma N.; Kappe, C. Oliver
Organic Letters, 2011 , vol. 13, # 5 p. 984 - 987
反应条件
sulfuric acid in methanol T=25°C; Kinetics; Further Variations:reagent concentrations;
参考文献
Pytela, Oldrich; Trlida, Bronislav
Collection of Czechoslovak Chemical Communications, 2007 , vol. 72, # 8 p. 1025 - 1036
反应条件
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 °C / |Schlenk technique; |Inert atmosphere 2: [Pd2H2(1,3-bis(diphenylphosphino)propane)3](TfO)2 / tetrahydrofuran / 24 h / 100 °C / |Schlenk technique; |Inert atmosphere; |Glovebox View Scheme
参考文献
Vyas, Devendra J.; Larionov, Evgeny; Besnard, Celine; Guenee, Laure; Mazet, Clement
Journal of the American Chemical Society, 2013 , vol. 135, # 16 p. 6177 - 6183
反应条件
ozone in methanol T=20°C; 3.45 h;
参考文献
O'Brien, Matthew; Baxendale, Ian R.; Ley, Steven V.
Organic Letters, 2010 , vol. 12, # 7 p. 1596 - 1598
反应条件
1: 2-methyl-2-(4-fluorophenyl)-ethene With ozone in methanol T=20°C; 2: methanol With dihydrogen peroxide T=20°C;
参考文献
Irfan, Muhammad; Glasnov, Toma N.; Kappe, C. Oliver
Organic Letters, 2011 , vol. 13, # 5 p. 984 - 987
