2,4,5-三氨基-6-羟基嘧啶硫酸盐合成路线 （共 19 条）
反应条件
piperidine in water T=20°C; 168 h;
参考文献
Zav'yalov, S. I.; Ezhova, G. I.; Budkova, T. K.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1984 , vol. 33, # 7 p. 1459 - 1462
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1984 , # 7 p. 1590 - 1593
反应条件
piperidine in water T=20°C; 165 h;
参考文献
Zav'yalov, S. I.; Zavoshin, A. G.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 2 p. 419 - 422
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 2 p. 452 - 455
反应条件
triethylamine in water; N,N-dimethyl-formamide T=20°C; 165 h;
参考文献
Zav'yalov, S. I.; Zavoshin, A. G.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 2 p. 419 - 422
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 2 p. 452 - 455
反应条件
piperidine; sodium carbonate in hydrogenchloride; water T=20°C; 144 h;
参考文献
Zav'yalov, S. I.; Ezhova, G. I.; Budkova, T. K.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1984 , vol. 33, # 7 p. 1459 - 1462
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1984 , # 7 p. 1590 - 1593
反应条件
piperidine in water T=20°C; 144 h;
参考文献
Zav'yalov, S. I.; Zavozin, A. G.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 7 p. 1355 - 1357
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , # 7 p. 1666 - 1668
反应条件
sodium disulfite in water T=80°C; 6 h; further cyclizating agents; Product distribution;
参考文献
Zav'yalov, S. I.; Zavoshin, A. G.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 2 p. 419 - 422
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 2 p. 452 - 455
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 9 p. 3608 - 3615
反应条件
1: With pyridine; sodium dithionite; sodium acetate in methanol; water T=35 - 40°C; 20 h; Inert atmospheresealed vesselyellow light; 2: With iodine in methanol; water 3: With ammonium hydroxide in methanol; water T=50°C; 1 h;
参考文献
KANEKA CORPORATION
Patent: US2011/218339 A1, 2011 ;
Location in patent: Page/Page column 4 ;
反应条件
Yield given. Multistep reaction;
参考文献
Mori, Kenji; Kikuchi, Haruhiko
Liebigs Annalen der Chemie, 1989 , p. 963 - 968
