N-苄氧羰基-亮氨酰-亮氨酸甲酯合成路线 （共 20 条）
反应条件
3,3'-Dicyano-4,4',6,6'-tetramethyl-2,2'-dipyridinyl-disulfid; triphenylphosphine in dichloromethane T=-20 - -15°C; 12 h;
参考文献
Schmidt, Ulrich; Potzolli, Bernd
Liebigs Annalen der Chemie, 1987 , p. 935 - 942
反应条件
Sephadex G-50; triethylamine; bromelain in ethyl acetate T=37°C; 7 h;
参考文献
Tai, Dar-Fu; Fu, Shu-Lin
Journal of the Chinese Chemical Society, 2003 , vol. 50, # 1 p. 179 - 183
反应条件
triethylamine in dichloromethane T=20°C; 22 h;
参考文献
Freund, Matthias H.; Tsogoeva, Svetlana B.
Synlett, 2011 , # 4 p. 503 - 507
反应条件
tetraethyl pyrophosphite
参考文献
Vaughan; Osato
Journal of the American Chemical Society, 1952 , vol. 74, p. 676
反应条件
1: 1.) 4N NaOH / 1.) ca 5 deg C, 15 min 2.) ethyl acetate, Et2O, 5 min 2: 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide / CH2Cl2 / 2 h / temperature: below 0 deg C View Scheme
参考文献
Herlinger,H. et al.
Justus Liebigs Annalen der Chemie, 1967 , vol. 706, p. 37 - 46
反应条件
1: 1.) 4N NaOH / 1.) ca 5 deg C, 15 min 2.) ethyl acetate, Et2O, 5 min 2: 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide / CH2Cl2 / 2 h / temperature: below 0 deg C View Scheme
参考文献
Herlinger,H. et al.
Justus Liebigs Annalen der Chemie, 1967 , vol. 706, p. 37 - 46
反应条件
diethyl ether; chloroform
参考文献
Nyman; Herbst
Journal of Organic Chemistry, 1950 , vol. 15, p. 108,115
Full Text Show Details
Smith et al.
Journal of Biological Chemistry, 1952 , vol. 199, p. 801,808
反应条件
sodium dioctyl sulfosuccinate in 2,2,4-trimethylpentane; water 48 h; Product distribution;
参考文献
Ranganathan, D.; Singh, G. P.; Ranganathan, S.
Journal of the American Chemical Society, 1989 , vol. 111, # 3 p. 1144 - 1145
反应条件
benzotriazol-1-ol; dicyclohexyl-carbodiimide in dichloromethane 2 h; temperature: below 0 deg C;
参考文献
Hoogwater, D. A.; Peereboom, M.
Tetrahedron, 1990 , vol. 46, # 15 p. 5325 - 5332
反应条件
4-methyl-morpholine in tetrahydrofuran 0.5 h;
参考文献
Zhu, Yun-Fei; Fuller, William D.
Tetrahedron Letters, 1995 , vol. 36, # 6 p. 807 - 810
