5-氯-2-甲基-3-吡啶羧酸甲酯合成路线

参考文献

COMENTIS, INC.; PURDUE RESEARCH FOUNDATION
Patent: WO2009/42694 A1, 2009 ;
Location in patent: Page/Page column 106-107 ;
WO 2009/042694 A1

325855-84-3

350597-49-85-氯-2-甲基-3-吡啶羧酸甲酯

参考文献

Marcoux; Marcotte; Wu; Dormer; Davies; Hughes; Reider
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4194 - 4199

105-45-3乙酰乙酸甲酯

350597-49-85-氯-2-甲基-3-吡啶羧酸甲酯

参考文献

Journal of Organic Chemistry, , vol. 66, # 12 p. 4194 - 4199

350597-49-85-氯-2-甲基-3-吡啶羧酸甲酯

917878-65-07-溴-3-氯-5H-苯并[4,5]环庚基[1,2-b]吡啶-5-酮

参考文献

Katz, Jason D.; Jewell, James P.; Guerin, David J.; Lim, Jongwon; Dinsmore, Christopher J.; Deshmukh, Sujal V.; Pan, Bo-Sheng; Marshall, C. Gary; Lu, Wei; Altman, Michael D.; Dahlberg, William K.; Davis, Lenora; Falcone, Danielle; Gabarda, Ana E.; Hang, Gaozhen; Hatch, Harold; Holmes, Rachael; Kunii, Kaiko; Lumb, Kevin J.; Lutterbach, Bart; Mathvink, Robert; Nazef, Naim; Patel, Sangita B.; Qu, Xianlu; Reilly, John F.; Rickert, Keith W.; Rosenstein, Craig; Soisson, Stephen M.; Spencer, Kerrie B.; Szewczak, Alexander A.; Walker, Deborah; Wang, Wenxian; Young, Jonathan; Zeng, Qinwen
Journal of Medicinal Chemistry, 2011 , vol. 54, # 12 p. 4092 - 4108

1122-91-44-溴苯甲醛+

350597-49-85-氯-2-甲基-3-吡啶羧酸甲酯

917942-73-52-[(E)-2-(4-溴苯基)乙烯基]-5-氯烟酸

参考文献

Katz, Jason D.; Jewell, James P.; Guerin, David J.; Lim, Jongwon; Dinsmore, Christopher J.; Deshmukh, Sujal V.; Pan, Bo-Sheng; Marshall, C. Gary; Lu, Wei; Altman, Michael D.; Dahlberg, William K.; Davis, Lenora; Falcone, Danielle; Gabarda, Ana E.; Hang, Gaozhen; Hatch, Harold; Holmes, Rachael; Kunii, Kaiko; Lumb, Kevin J.; Lutterbach, Bart; Mathvink, Robert; Nazef, Naim; Patel, Sangita B.; Qu, Xianlu; Reilly, John F.; Rickert, Keith W.; Rosenstein, Craig; Soisson, Stephen M.; Spencer, Kerrie B.; Szewczak, Alexander A.; Walker, Deborah; Wang, Wenxian; Young, Jonathan; Zeng, Qinwen
Journal of Medicinal Chemistry, 2011 , vol. 54, # 12 p. 4092 - 4108