4-(4-氯苯基)-2-丁酮合成路线 （共 19 条）
反应条件
bismuth trifluoromethanesulphonate; ammonium chloride; malononitrile in dichloromethane T=20°C; 50 h; regioselective reaction;
参考文献
Shang, Jun-Yan; Li, Fei; Bai, Xing-Feng; Jiang, Jian-Xiong; Yang, Ke-Fang; Lai, Guo-Qiao; Xu, Li-Wen
European Journal of Organic Chemistry, 2012 , # 14 p. 2809 - 2815
反应条件
4,4'-diphenylsulfide; hydrogen; palladium on activated charcoal in methanol T=20°C; P=760 Torr; 24 h;
参考文献
Mori, Akinori; Mizusaki, Tomoteru; Miyakawa, Yumi; Ohashi, Eri; Haga, Tomoko; Maegawa, Tomohiro; Monguchi, Yasunari; Sajiki, Hironao
Tetrahedron, 2006 , vol. 62, # 51 p. 11925 - 11932
反应条件
potassium carbonate in ethanol 16 h; Heating / reflux;
参考文献
THE JOHNS HOPKINS UNIVERSITY
Patent: WO2008/124132 A1, 2008 ;
Location in patent: Page/Page column 54 ;
反应条件
tetrabutyl-ammonium chloride; sodium hydrogencarbonate in N,N-dimethyl-formamide T=100°C; Heck Reaction; 5 h; Inert atmosphere; regioselective reaction;
参考文献
Huang, Yixiang; Wang, Pingping; Liu, Jiaqin; Cai, Mingzhong
Journal of Chemical Research, 2013 , vol. 37, # 6 p. 333 - 336
反应条件
cyclooctadiene in methanol T=65°C; 8 h; Inert atmosphere;
参考文献
Kantam, Mannepalli Lakshmi; Subrahmanyam, Vura Bala; Kumar, Kota Balaji Shiva; Venkanna, Gopaladasu T.; Sreedhar, Bojja
Helvetica Chimica Acta, 2008 , vol. 91, # 10 p. 1947 - 1953
反应条件
in diethyl ether T=0 - 20°C;
参考文献
SEPRACOR INC.
Patent: US2005/143443 A1, 2005 ;
Location in patent: Page/Page column 30 ;
反应条件
RuCl3H(p-cymene)2; immobilized lipase from Pseudomonas cepacia; triethylamine in dichloromethane T=20 - 25°C; Acetylation; oxidation; reduction; 48 h; Enzymatic reaction;
参考文献
Lee; Huh; Kim; Jung; Koh; Park
Organic letters, 2000 , vol. 2, # 15 p. 2377 - 2379
反应条件
[RhCl(η2:η2-cycloocta-1,5-diene)]2 in N-methyl-2-pyrrolidinone; water T=100°C; 1 h;
参考文献
Kakusawa, Naoki; Yasuike, Shuji; Kurita, Jyoji
Heterocycles, 2009 , vol. 77, # 2 p. 1269 - 1283
反应条件
1,3-bis-(diphenylphosphino)propane; triethylamine; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide T=150°C; 6 h; sealed tube;
参考文献
Hagiwara, Hisahiro; Eda, Yasushi; Morohashi, Kimie; Suzuki, Toshio; Ando, Masayoshi; Ito, Nobuhiko
Tetrahedron Letters, 1998 , vol. 39, # 23 p. 4055 - 4058
反应条件
RhH(CO)(triphenylphosphine)3 in methanol T=60°C; P=30002.4 Torr; 18 h;
参考文献
Chemical Communications, , # 13 p. 1520 - 1521
