1-[3-(苯甲酸基)丙基]-2,3-二氢-5-(2-硝基丙基)-1H-吲哚-7-甲腈合成路线 （共 12 条）
反应条件
1: hydrogenchloride; zinc / water; methanol / 20 h / 60 - 65 °C 2: water; tetrahydrofuran / 20 - 65 °C View Scheme
参考文献
PANACEA BIOTEC LTD; JAIN, Rajesh; RAO, Jagadeeshwar R; RAO, Siripragada Mahender
Patent: WO2012/131710 A2, 2012 ;
反应条件
1: platinum on carbon; hydrogen / ethyl acetate / 25 - 30 °C / 6000.6 - 7500.75 Torr / |Autoclave 2: acetone; water / 25 - 65 °C / |Resolution of racemate View Scheme
参考文献
SANDOZ AG; KUMAR LUTHRA, Parven; BHUTA, Sachin; ABHINAY, Chandrakant Pise; DATTATRAYA, N., Chavan; SHASHIKANT, D., Metkar
Patent: WO2013/56842 A1, 2013 ;
