3,5-二乙酰氧基苯乙酮合成路线 （共 12 条）
反应条件
tris(dibezoylmethanato)Fe(III) in tetrahydrofuran T=-15°C; Grignard Reaction; 0.5 h; Inert atmosphere; Product distribution / selectivity;
参考文献
DSM IP Assets B.V.
Patent: EP2404891 A1, 2012 ;
Location in patent: Page/Page column 5 ;
反应条件
aluminum triflate T=20°C; 0.00555556 h;
参考文献
Kamal, Ahmed; Khan, M. Naseer A.; Reddy, K. Srinivasa; Srikanth; Krishnaji
Tetrahedron Letters, 2007 , vol. 48, # 22 p. 3813 - 3818
反应条件
1: pyridine / 100 °C 2: thionyl chloride / dichloromethane / Reflux 3: iron(III) tris(dibenzoylmethane) / tetrahydrofuran / -15 °C / Inert atmosphere View Scheme
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 115, p. 277
参考文献
Bulletin des Societes Chimiques Belges, , vol. 65, p. 596,602
反应条件
bromine in carbon disulfide
参考文献
Otsuka Pharmaceutical Co., Ltd.
Patent: US5643932 A1, 1997 ;
反应条件
bromine; acetic acid T=20°C; 1 h;
参考文献
Taketomi, Shohei; Asano, Masayoshi; Higashi, Toshinori; Shoji, Mitsuru; Sugai, Takeshi
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 84, p. 83 - 88
反应条件
1: With bromine in chloroform 0.5 h; 2: With hydrogen bromide in ethanol 0.5 h; Heating; Further stages.;
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 20 p. 5003 - 5011
反应条件
aluminum oxide in neat (no solvent) T=80°C; 0.0666667 h; microwave irradiation;
参考文献
Varma, Rajender S.; Varma, Manju; Chatterjee, Arnab K.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 9 p. 999 - 1000
反应条件
1: immobilized Burkholderia cepacia lipase (Amano PS-IM) / isopropyl alcohol; tetrahydrofuran / 60 h / 20 °C / |Inert atmosphere; |Enzymatic reaction
2: potassium carbonate / N,N-dimethyl-formamide / 6.5 h / 20 °C
3: bromine / acetic acid / 1.17 h / 0 - 20 °C
View Scheme
参考文献
Asami, Kento; Machida, Takuya; Jung, Sonna; Hanaya, Kengo; Shoji, Mitsuru; Sugai, Takeshi
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 97, p. 106 - 109
