5-(甲氧基)噻吩-2-羧醛合成路线 （共 6 条）
反应条件
1: 2-methoxy-thiophene With n-butyllithium in diethyl ether; hexane T=0°C; 1 h; 2: N,N-dimethyl-formamide in diethyl ether; hexane 1 h; Heating; Further stages.;
参考文献
Batista, Rosa M.F.; Costa, Susana P.G.; Belsley; Lodeiro, Carlos; Raposo, M. Manuela M.
Tetrahedron, 2008 , vol. 64, # 39 p. 9230 - 9238
反应条件
diethyl ether anschliessend Behandeln mit Eis;
参考文献
Sice
Journal of the American Chemical Society, 1953 , vol. 75, p. 3697,3699
反应条件
trichlorophosphate T=80°C; 1 h;
参考文献
Costa, Susana P.G.; Ferreira, Joao A.; Kirsch, Gilbert; Oliveira-Campos, Ana M.F.
Journal of Chemical Research, Miniprint, 1997 , # 9 p. 2001 - 2013
反应条件
trichlorophosphate Behandeln mit 2-Methoxy-thiophen und anschliessend mit Eis;
参考文献
Profft
Justus Liebigs Annalen der Chemie, 1959 , vol. 622, p. 196,198
反应条件
Yield given. Multistep reaction;
参考文献
Downie, Ian M.; Earle, Martyn J.; Heaney, Harry; Shuhaibar, Khamis F.
Tetrahedron, 1993 , vol. 49, # 19 p. 4015 - 4034
反应条件
hydroxylamine hydrochloride; sodium acetate in acetic acid
T=100°C; 11 h;
参考文献
Asahi Kasei Pharma Corporation
Patent: WO2006/123639 A1, 2006 ;
Location in patent: Page/Page column 133 ;
WO 2006/123639 A1
