5-溴-2-羟基-3-甲氧基苯甲酸合成路线 （共 6 条）
反应条件
sodium hypochlorite; aminosulfonic acid in tetrahydrofuran; water T=20°C; 3 h;
参考文献
Magnin, David R.; Sulsky, Richard B.; Robl, Jeffrey A.; Caulfield, Thomas J.; Parker, Rex A.
Patent: US2003/225091 A1, 2003 ;
Location in patent: Page 63 ;
反应条件
pyridine; bromine in chloroform 1 h;
参考文献
Lu, S.; Adam, M. J.; Lu, J.; Ruth, T. J.
Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, p. S234 - S234
反应条件
boron tribromide in dichloromethane T=0 - 20°C;
参考文献
Magnin, David R.; Sulsky, Richard B.; Robl, Jeffrey A.; Caulfield, Thomas J.; Parker, Rex A.
Patent: US2003/225091 A1, 2003 ;
Location in patent: Page 63 ;
反应条件
1: dimethylformamide, thionyl chloride / toluene / 1 h / 65 °C 2: CH2Cl2 / Ambient temperature View Scheme
参考文献
Hogberg; De Paulis; Johansson; Kumar; Hall; Ogren
Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2305 - 2309
反应条件
dicyclohexyl-carbodiimide in chloroform
参考文献
Lu, S.; Adam, M. J.; Lu, J.; Ruth, T. J.
Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, p. S234 - S234
反应条件
sulfuric acid 18 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 14 p. 3194 - 3204
