3-(4-氯苯基)-1H-吡唑-4-甲醛合成路线 (共 5 条)
反应条件
1: With trichlorophosphate T=65°C; Vilsmeier-Haack reaction; 6.5 h; Cooling with ice; 2: With sodium hydroxide in water pH=7; Cooling with ice;
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 11 p. 5591 - 5597
反应条件
trichlorophosphate T=40 - 80°C; Vilsmeier formylation;
参考文献
Russian Journal of General Chemistry, , vol. 75, # 5 p. 782 - 789
反应条件
1.1: AcONa / ethanol / 0.75 h / Heating 1.2: ethanol / 1 h / Heating 2.1: 32 percent / POCl3 / 40 - 80 °C View Scheme
参考文献
Russian Journal of General Chemistry, , vol. 75, # 5 p. 782 - 789
反应条件
1: With trichlorophosphate 2: With sodium hydroxide; water
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 18 p. 4932 - 4935
反应条件
sodium hydroxide; potassium permanganate in water T=20 - 98°C;
参考文献
Lebedev; Lebedeva; Sheludyakov; Kovaleva; Ustinova; Kozhevnikov
Russian Journal of General Chemistry, 2005 , vol. 75, # 5 p. 782 - 789