1-(2-氨基苯基)-2,2,2-三氟乙烷酮合成路线 （共 3 条）
反应条件
1,10-phenanthroline; diethyl 1,2-hydrazinedicarboxylate; oxygen; potassium carbonate; copper(l) chloride in toluene T=90°C; 1 h;
参考文献
Kim, Dae-Sik; Chung, Yun-Mi; Jun, Mieun; Ahn, Kyo Han
Journal of Organic Chemistry, 2009 , vol. 74, # 13 p. 4849 - 4854
反应条件
1: With hydrogenchloride; water T=25 - 75°C; 2: With sodium hydrogencarbonate in water; ethyl acetate
参考文献
Zhu, Lingjian; Miao, Zhenyuan; Sheng, Chunquan; Yao, Jianzhong; Zhuang, Chunlin; Zhang, Wannian
Journal of Fluorine Chemistry, 2010 , vol. 131, # 7 p. 800 - 804
反应条件
1: 98 percent / H2 / Pd/C / methanol / 2 h / 25 °C 2: 55 percent / MnO2 / CH2Cl2 / 0.5 h / 25 °C View Scheme
参考文献
Patel, Mona; Ko, Soo S.; McHugh Jr., Robert J.; Markwalder, Jay A.; Srivastava, Anurag S.; Cordova, Beverly C.; Klabe, Ronald M.; Erickson-Viitanen, Susan; Trainor, George L.; Seitz, Steven P.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 19 p. 2805 - 2810
