2-亚甲基-1,3-丙二醇合成路线 （共 25 条）
反应条件
tetra-(n-butyl)ammonium iodide; sodium hydride in N,N-dimethyl-formamide T=40°C;
参考文献
Kim, Hea Ok; Baek, Hye Won; Moon, Hyung Ryong; Kim, Dae-Kee; Chun, Moon Woo; Jeong, Lak Shin
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 8 p. 1164 - 1168
反应条件
1: 1-hydroxy-2-hydroxymethyl-2-propene With sodium hydride in tetrahydrofuran; mineral oil T=0°C; 0.5 h; Inert atmosphere; 2: benzyl bromide With tetra-(n-butyl)ammonium iodide in tetrahydrofuran; mineral oil T=0 - 20°C; Inert atmosphere; 3: With water in tetrahydrofuran; mineral oil T=0°C; Inert atmosphere;
参考文献
Russo, Francesco; Wangsell, Fredrik; Saevmarker, Jonas; Jacobsson, Micael; Larhed, Mats
Tetrahedron, 2009 , vol. 65, # 48 p. 10047 - 10059
参考文献
N.V. de Bataafsche Petr.Mij.
Patent: DE632571 , 1933 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 23, p. 112
参考文献
N.V. de Bataafsche Petr.Mij.
Patent: DE632571 , 1933 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 23, p. 108
参考文献
Burchardt; Takahashi; Takeuchi; Haufe
Journal of Organic Chemistry, 2001 , vol. 66, # 6 p. 2078 - 2084
反应条件
pyridine; thionyl chloride in dichloromethane 3 h; Reflux;
参考文献
WO2012/67663 A1, ;
Page/Page column 41 ;
反应条件
2,2'-azo-bisisobutyronitrile in neat (no solvent)
mixt. of educts and AIBN warmed under Ar for 5 h at 64°C; crystd. (hexanes/C6H6); elem. anal.;
参考文献
Ducharme, Yves; Latour, Stephan; Wuest, James D.
Organometallics, 1984 , vol. 3, p. 208 - 211
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine in dichloromethane
T=20°C; 16 h;
参考文献
Or, Yat Sun; Qiu, Yao-Ling; Wang, Guoqiang; Niu, Deqiang; Phan, Ly Tam
Patent: US2006/69048 A1, 2006 ;
Location in patent: Page/Page column 52 ;
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane
T=20°C; 16 h;
参考文献
Cortijos, Andrea March; Snape, Timothy J.
Tetrahedron Asymmetry, 2008 , vol. 19, # 15 p. 1761 - 1763
反应条件
triethylamine in dichloromethane; ethyl acetate
参考文献
The Trustees of Columbia University in the City of New York
Patent: US7883869 B2, 2011 ;
