(1R,2R)-(+)-1,2-二苯基乙二胺合成路线 (共 30 条)
反应条件
1: (i) NaN3, Fe2(SO4)3, (ii) H2O2, (iii) Sn, aq. HCl View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 102, p. 855 - 892
反应条件
triethylamine in dichloromethane
参考文献
Journal of Organic Chemistry, , vol. 73, # 13 p. 4903 - 4906
反应条件
4-(N,N-dimethlyamino)pyridine in acetonitrile T=20°C; 24 h;
参考文献
Suzuki, Ichiro; Ando, Masafumi; Shimabara, Rumiko; Hirata, Ai; Takeda, Kei
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 8 p. 3033 - 3040
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 2 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 347, # 1 p. 61 - 77
反应条件
n-butyllithium in tetrahydrofuran; hexane T=0 - 20°C; Haller-Bauer reaction; 6 h;
参考文献
Ishihara, Kazuaki; Yano, Takayuki
Organic Letters, 2004 , vol. 6, # 12 p. 1983 - 1986
反应条件
triethylamine in tetrahydrofuran 12 h;
参考文献
Shankaraiah, Nagula; da Silva, Wender A.; Andrade, Carlos Kleber Z.; Santos, Leonardo Silva
Tetrahedron Letters, 2008 , vol. 49, # 27 p. 4289 - 4291
反应条件
N-bromosuccinmide in dichloromethane T=0 - 20°C;
参考文献
Fujioka, Hiromichi; Murai, Kenichi; Ohba, Yusuke; Hiramatsu, Atsushi; Kita, Yasuyuki
Tetrahedron Letters, 2005 , vol. 46, # 13 p. 2197 - 2199
反应条件
in ethanol r.t., 1 h then reflux, 4 h;
参考文献
Dauwe; Buddrus
Synthesis, 1995 , # 2 p. 171 - 172
反应条件
1,3-bis-(diphenylphosphino)propane; caesium carbonate; palladium dichloride in toluene 16 h; Inert atmosphereReflux;
参考文献
Geden, Joanna V.; Pancholi, Alpa K.; Shipman, Michael
Journal of Organic Chemistry, 2013 , vol. 78, # 8 p. 4158 - 4164
反应条件
triethylamine in dichloromethane
参考文献
Stones, Graham; Tripoli, Regis; McDavid, Colin L.; Roux-Duplgtre, Kewin; Kennedy, Alan R.; Sherrington, David C.; Gibson, Colin L.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 2 p. 374 - 384