tetrabutyl-ammonium chloride; palladium diacetate; potassium carbonate in water; N,N-dimethyl-formamide T=70°C; Inert atmosphere; stereoselective reaction;

1: (E)-3-(benzo[1,3]dioxol-5-yl)acrylic acid With N-bromosuccinmide; tetrabutyl-ammonium trifluoroacetate in 1,2-dichloro-ethane T=20°C; Decarboxylation; bromination; Hunsdiecker reaction; 4 h; 2: N-(2-methylpropyl)prop-2-enamide With palladium diacetate; tri-phenyl-antimony; triethylamine in 1,2-dichloro-ethane Heck reaction; 20 h;