(E)-9-十二碳烯-1-醇乙酸酯合成路线 （共 50 条）
反应条件
1: 92.3 percent / LiAlH4 / diethyl ether 2: 92.9 percent / pyridine / benzene View Scheme
参考文献
Singh, Krishna Nand; Singh, Manorama; Misra, Ram Achal
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 4 p. 431 - 434
反应条件
1: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C 2: acetic acid / 10 h / 50 °C View Scheme
参考文献
Oprean, I.; Ciupe, Hilke; Gansca, Lucia; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 2 p. 283 - 289
反应条件
1: (AcO)2Cu / acetic acid; H2O / 0.67 h / Heating 2: 85percent hydrazine hydrate / butan-1-ol / Heating 3: O2, CuCl / pyridine 4: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C 5: acetic acid / 10 h / 50 °C View Scheme
参考文献
Oprean, I.; Ciupe, Hilke; Gansca, Lucia; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 2 p. 283 - 289
反应条件
1: 85percent hydrazine hydrate / butan-1-ol / Heating 2: O2, CuCl / pyridine 3: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C 4: acetic acid / 10 h / 50 °C View Scheme
参考文献
Oprean, I.; Ciupe, Hilke; Gansca, Lucia; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 2 p. 283 - 289
反应条件
1: O2, CuCl / pyridine 2: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C 3: acetic acid / 10 h / 50 °C View Scheme
参考文献
Oprean, I.; Ciupe, Hilke; Gansca, Lucia; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 2 p. 283 - 289
反应条件
1: 46 percent / PBr3 / diethyl ether / 2 h / -15 °C 2: 1) Mg, I2, 2) HMPT / 1) THF, 2 h, reflux, 2) THF, 12 h 3: acetic acid / 16 h / 40 °C 4: 98 percent / urea / methanol / 16 h / Ambient temperature View Scheme
参考文献
Popovici, N.; Botar, A. A.; Barabas, A.; Oprean, I.; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1983 , vol. 325, # 1 p. 17 - 26
反应条件
1: 1) Mg, I2, 2) HMPT / 1) THF, 2 h, reflux, 2) THF, 12 h 2: acetic acid / 16 h / 40 °C 3: 98 percent / urea / methanol / 16 h / Ambient temperature View Scheme
参考文献
Popovici, N.; Botar, A. A.; Barabas, A.; Oprean, I.; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1983 , vol. 325, # 1 p. 17 - 26
反应条件
1: 1.) BuLi / 1.) THF, hexane, 2 h, -20 deg C, 2.) 30 min, -78 degC 2: LiAlH4 / diethyl ether / 1 h / 0 °C 3: p-toluenesulfonic acid / methanol; H2O / 3 h / Heating 4: 72 percent / pyridine / 1 h / Heating View Scheme
参考文献
Canevet; Roeder; Vostrowsky; Bestmann
Chemische Berichte, 1980 , vol. 113, # 3 p. 1115 - 1120
反应条件
1: LiAlH4 / diethyl ether / 1 h / 0 °C 2: p-toluenesulfonic acid / methanol; H2O / 3 h / Heating 3: 72 percent / pyridine / 1 h / Heating View Scheme
参考文献
Canevet; Roeder; Vostrowsky; Bestmann
Chemische Berichte, 1980 , vol. 113, # 3 p. 1115 - 1120
反应条件
1: 1) butyl lithium, diisopropylamine / 1) ether, 1h, 2) 6h, reflux 2: 95 percent / triethylamine / CH2Cl2 / 0.5 h / 0 °C 3: 1) CuI2 / 1) ether, -10 deg C, 10min, 2) 0 deg C, 4h 3) r.t. 4: 90 percent / PTS / methanol / 4 h 5: pyridine / Ambient temperature View Scheme
参考文献
Vig, O. P.; Sharma, M. L.; Verma, N. K.; Malik, Neera
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 8 p. 692 - 694
