反-10-十二烯醇乙酸酯合成路线 （共 15 条）
反应条件
acetic acid T=50 - 55°C; 48 h;
参考文献
Gansca, Lucia; Gocan, Alexandra; Oprean, Ioan
Revue Roumaine de Chimie, 1994 , vol. 39, # 7 p. 821 - 826
反应条件
pyridine; acetic acid
参考文献
Vig; Sharma; Sabharwal; Gupta; Huq
Journal of the Indian Chemical Society, 1990 , vol. 67, # 1 p. 34 - 36
反应条件
1: conc. HCl / 3 h / 20 °C 2: 1.) LiNH2 / 1.) liq. NH3, 1 h, 2.) THF, 3 h 3: 16percent H2SO4 / ethanol / 1 h / 50 °C 4: 95 percent / LiAlH4 / bis-(2-methoxy-ethyl) ether / 48 h / 140 °C 5: 7.3 g / pyridine / diethyl ether View Scheme
参考文献
Ishchenko
Chemistry of Natural Compounds, 1996 , vol. 32, # 1 p. 77 - 79
反应条件
1: 85 percent / LiAlH4 / diethyl ether / 3 h / 40 °C 2: conc. HCl / 3 h / 20 °C 3: 1.) LiNH2 / 1.) liq. NH3, 1 h, 2.) THF, 3 h 4: 16percent H2SO4 / ethanol / 1 h / 50 °C 5: 95 percent / LiAlH4 / bis-(2-methoxy-ethyl) ether / 48 h / 140 °C 6: 7.3 g / pyridine / diethyl ether View Scheme
参考文献
Ishchenko
Chemistry of Natural Compounds, 1996 , vol. 32, # 1 p. 77 - 79
反应条件
1: 1.) Br2, 2.) Na / 1.) Et2O, -20 deg C, 2.) liq. NH3, 30 min 2: 85 percent / LiAlH4 / diethyl ether / 3 h / 40 °C 3: conc. HCl / 3 h / 20 °C 4: 1.) LiNH2 / 1.) liq. NH3, 1 h, 2.) THF, 3 h 5: 16percent H2SO4 / ethanol / 1 h / 50 °C 6: 95 percent / LiAlH4 / bis-(2-methoxy-ethyl) ether / 48 h / 140 °C 7: 7.3 g / pyridine / diethyl ether View Scheme
参考文献
Ishchenko
Chemistry of Natural Compounds, 1996 , vol. 32, # 1 p. 77 - 79
反应条件
1: 95 percent / LiAlH4 / bis-(2-methoxy-ethyl) ether / 48 h / 140 °C 2: 7.3 g / pyridine / diethyl ether View Scheme
参考文献
Ishchenko
Chemistry of Natural Compounds, 1996 , vol. 32, # 1 p. 77 - 79
反应条件
1: 1.) LiNH2 / 1.) liq. NH3, 1 h, 2.) THF, 3 h 2: 16percent H2SO4 / ethanol / 1 h / 50 °C 3: 95 percent / LiAlH4 / bis-(2-methoxy-ethyl) ether / 48 h / 140 °C 4: 7.3 g / pyridine / diethyl ether View Scheme
参考文献
Ishchenko
Chemistry of Natural Compounds, 1996 , vol. 32, # 1 p. 77 - 79
反应条件
1: 16percent H2SO4 / ethanol / 1 h / 50 °C 2: 95 percent / LiAlH4 / bis-(2-methoxy-ethyl) ether / 48 h / 140 °C 3: 7.3 g / pyridine / diethyl ether View Scheme
参考文献
Ishchenko
Chemistry of Natural Compounds, 1996 , vol. 32, # 1 p. 77 - 79
反应条件
1: 87 percent / KOH / ethane-1,2-diol / 50 h / 160 - 165 °C 2: 80 percent / LiAlH4 / tetrahydrofuran; bis-(2-methoxy-ethyl) ether / 20 h / 145 °C 3: 68 percent / gl. AcOH / 48 h / 50 - 55 °C View Scheme
参考文献
Gansca, Lucia; Gocan, Alexandra; Oprean, Ioan
Revue Roumaine de Chimie, 1994 , vol. 39, # 7 p. 821 - 826
反应条件
1: 1.) NaH / 1.) DMSO, 20-30 deg C, 2.) DMSO, RT, 3 h 2: 87 percent / KOH / ethane-1,2-diol / 50 h / 160 - 165 °C 3: 80 percent / LiAlH4 / tetrahydrofuran; bis-(2-methoxy-ethyl) ether / 20 h / 145 °C 4: 68 percent / gl. AcOH / 48 h / 50 - 55 °C View Scheme
参考文献
Gansca, Lucia; Gocan, Alexandra; Oprean, Ioan
Revue Roumaine de Chimie, 1994 , vol. 39, # 7 p. 821 - 826
