2'-羟基-3-苯基苯丙酮合成路线 （共 38 条）
反应条件
sodium hydroxide 18 h; Reflux;
参考文献
Lowes, David J.; Guiguemde, W. Armand; Connelly, Michele C.; Zhu, Fangyi; Sigal, Martina S.; Clark, Julie A.; Lemoff, Andrew S.; Derisi, Joseph L.; Wilson, Emily B.; Guy, R. Kiplin
Journal of Medicinal Chemistry, 2011 , vol. 54, # 21 p. 7477 - 7485
反应条件
1: 40 percent / PhI(OAc)2, KOH / 0 degC -> room temp. 2: dilute H2SO4 / Heating View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 20 p. 1342 - 1343
反应条件
hydrogenchloride; triphenylphosphine
参考文献
BASF Aktiengesellschaft
Patent: US4945114 A1, 1990 ;
反应条件
hydrogenchloride; NaH in tetrahydrofuran; propylamine; ethanol
参考文献
BASF Aktiengesellschaft
Patent: US4945114 A1, 1990 ;
反应条件
1: ammonia / methanol / 2 h / 20 °C / Inert atmosphere
2: sodium hypochlorite / water; isopropyl alcohol / 0 - 10 °C / Inert atmosphere
View Scheme
参考文献
Chen, Cheng-Yi; Andreani, Teresa; Li, Hongmei
Organic Letters, 2011 , vol. 13, # 23 p. 6300 - 6303
参考文献
Di Paco; Tauro
Annali di Chimica (Rome, Italy), 1958 , vol. 48, p. 1215,1223
反应条件
1: 94 percent / toluene / 5 h / Heating
2: 73 percent / hydrogen / Pd/C / tetrahydrofuran / 20 °C / 760 Torr
View Scheme
参考文献
Kirkiacharian, B. Serge; Gomis, Michel
Synthetic Communications, 2005 , vol. 35, # 4 p. 563 - 569
反应条件
1: 40 percent / PhI(OAc)2, KOH / 0 degC -> room temp.
2: dilute H2SO4 / Heating
View Scheme
参考文献
Moriarty, Robert M.; Prakash, Om; Prakash, Indra; Musallam, H. A.
Journal of the Chemical Society, Chemical Communications, 1984 , # 20 p. 1342 - 1343
