1: N-(5-Chloro-pyridin-2-yl)-2,2-dimethylpropanamide With tert.-butyl lithium in tetrahydrofuran; pentane T=-78°C; 3 h; 2: 3-dimethylaminoacrylaldehyde in tetrahydrofuran; hexane T=-70 - 0°C; 3 h; 3: With hydrogenchloride T=80 - 90°C; 0.75 h;

1: tert-butyl 5-chloropyridin-2-ylcarbamate With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran; hexane T=-50°C; 1 h; 2: 3-dimethylaminoacrylaldehyde in tetrahydrofuran; hexane T=-70°C; 1.5 h; 3: With hydrogenchloride 3 h; Heating;