(2S)-2-氨基-5-(羟基氨基)戊酸合成路线 (共 3 条)
反应条件
<b>Multi-step reaction with 3 steps<br /> </b>1: (i) H<sub>2</sub>, Pd, MeOH, (ii) /BRN= 471382/<br />2: (i) MCPBA, CH<sub>2</sub>Cl<sub>2</sub>, (ii) ion-exchange resin <H<sup>+</sup> form><br />3: aq. HCl / methanol<br /> <br />
参考文献
Widmer; Keller-Schierlein Helvetica chimica acta, 1974 , vol. 57, # 3 p. 657 - 664
反应条件
<b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '1098214', constants.ctx, '0')">hydrogenchloride</a> <br /> <br />
参考文献
Isowa,Y. et al. Bulletin of the Chemical Society of Japan, 1972 , vol. 45, p. 1464 - 1466
反应条件
<b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '10414681', constants.ctx, '0')">NADPH tetrasodium salt</a>; <a href="#" onclick="return RXDsubstances(event, this, '5326842', constants.ctx, '0')">FAD</a> <br />T=25°C; pH=8.0; 12 h; TRIS bufferEnzymatic reaction; <br />
参考文献
Pohlmann, Verena; Marahiel, Mohamed A. Organic and Biomolecular Chemistry, 2008 , vol. 6, # 10 p. 1843 - 1848