6-氯-1-羟基-2-(三氟甲基)咪唑并[4,5-b]吡啶合成路线 (共 4 条)
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Cundy, Darren J.; Holan, George; Otaegui, Michelle; Simpson, Gregory W.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 6 p. 669 - 674
反应条件
1: 57 percent / HNO3, H2SO4 2: 83 percent / pyridine 3: 67 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Cundy, Darren J.; Holan, George; Otaegui, Michelle; Simpson, Gregory W.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 6 p. 669 - 674
反应条件
1: 83 percent / pyridine 2: 67 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Cundy, Darren J.; Holan, George; Otaegui, Michelle; Simpson, Gregory W.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 6 p. 669 - 674
反应条件
sulfuric acid; acetic anhydride
参考文献
Eli Lilly and Company
Patent: US3961937 A1, 1976 ;