4,4-二氟乙酰乙酸乙酯合成路线 （共 32 条）
反应条件
copper(l) chloride; zinc in tetrahydrofuran T=0 - 20°C; Reformatsky reaction; 2 h;
参考文献
Wang, Yanli; Zhu, Shizheng
Tetrahedron Letters, 2001 , vol. 42, # 33 p. 5741 - 5744
反应条件
copper(l) chloride; zinc in tetrahydrofuran T=0 - 20°C; Reformatsky reaction; 2 h;
参考文献
Wang, Yanli; Zhu, Shizheng
Tetrahedron Letters, 2001 , vol. 42, # 33 p. 5741 - 5744
反应条件
copper(l) chloride; zinc in tetrahydrofuran T=0 - 20°C; Reformatsky reaction; 2 h;
参考文献
Wang, Yanli; Zhu, Shizheng
Tetrahedron Letters, 2001 , vol. 42, # 33 p. 5741 - 5744
参考文献
WO2009/21987 A1, ;
Page/Page column 4 ;
反应条件
copper(l) chloride; zinc in tetrahydrofuran T=0 - 20°C; Reformatsky reaction; 2 h;
参考文献
Wang, Yanli; Zhu, Shizheng
Tetrahedron Letters, 2001 , vol. 42, # 33 p. 5741 - 5744
反应条件
copper(l) chloride; zinc in tetrahydrofuran T=0 - 20°C; Reformatsky reaction; 2 h;
参考文献
Tetrahedron Letters, , vol. 42, # 33 p. 5741 - 5744
反应条件
1.1: Caro's acid / ethanol / 24 h / 20 °C 2.1: triethylamine; sodium bicarbonate / CH2Cl2 / 1 h / Heating 2.2: pyrrolidine / CH2Cl2 / 2 h / Heating 2.3: aq. HCl / CH2Cl2 3.1: zinc dust; copper(I) chloride / tetrahydrofuran / 2 h / 0 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 33 p. 5741 - 5744
反应条件
1.1: triethylamine; sodium bicarbonate / CH2Cl2 / 1 h / Heating 1.2: pyrrolidine / CH2Cl2 / 2 h / Heating 1.3: aq. HCl / CH2Cl2 2.1: zinc dust; copper(I) chloride / tetrahydrofuran / 2 h / 0 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 33 p. 5741 - 5744
反应条件
1.1: triethylamine; sodium bicarbonate / CH2Cl2 / 1 h / Heating 1.2: pyrrolidine / CH2Cl2 / 2 h / Heating 1.3: aq. HCl / CH2Cl2 2.1: zinc dust; copper(I) chloride / tetrahydrofuran / 2 h / 0 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 33 p. 5741 - 5744
反应条件
1: ethyl acetate With n-butyllithium; diisopropylamine in diethyl ether T=-75°C; 0.333333 h; 2: CHF2COOEt in diethyl ether T=-75°C; 3 h;
参考文献
Russian Chemical Bulletin, , vol. 60, # 4 p. 733 - 745
