4-(1,3,4-噁二唑-2-基)苯胺合成路线 （共 11 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol T=20°C; P=760.051 Torr;
参考文献
AGIOS PHARMACEUTICALS, INC.; POPOVICI-MULLER, Janeta; SALITURO, Francesco, G.; SAUNDERS, Jeffrey, O.; TRAVINS, Jeremey; YAN, Shunqi
Patent: WO2012/9678 A1, 2012 ;
Location in patent: Page/Page column 221 ;
WO 2012/009678 A1
反应条件
hydrogen; palladium on activated charcoal in methanol P=760 Torr; 1 h; Ambient temperature;
参考文献
Bulletin de la Societe Chimique de France, , p. 1587 - 1591
反应条件
hydrogen; palladium on activated charcoal in methanol P=760 Torr; 1 h; Ambient temperature;
参考文献
Bulletin de la Societe Chimique de France, , p. 1587 - 1591
反应条件
2: phenylhydrazine / 150 °C View Scheme
参考文献
Zhurnal Obshchei Khimii, , vol. 29, p. 2027,2030; engl. Ausg. S. 1996, 1998
反应条件
1: xylene / 6.7 h / Heating 2: H2 / Pd-C / methanol / 1 h / 760 Torr / Ambient temperature View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 1587 - 1591
反应条件
1: hydrazine hydrate; methanol / 20 °C 2: Reflux 3: hydrogen / palladium 10 on activated carbon / methanol / 20 °C / 760.05 Torr View Scheme
参考文献
WO2012/9678 A1, ;
WO 2012/009678 A1
反应条件
1: sulfuric acid / Reflux 2: hydrazine hydrate; methanol / 20 °C 3: Reflux 4: hydrogen / palladium 10 on activated carbon / methanol / 20 °C / 760.05 Torr View Scheme
参考文献
WO2012/9678 A1, ;
WO 2012/009678 A1
反应条件
1: p-aminobenzoic acid methyl ester With hydrazine hydrate T=20°C; 2: trimethyl orthoformate 10 h; Heating;
参考文献
Magnetic Resonance in Chemistry, , vol. 41, # 9 p. 689 - 692
反应条件
1.1: SOCl2 2.1: hydrazine hydrate / 20 °C 2.2: 10 h / Heating View Scheme
参考文献
Magnetic Resonance in Chemistry, , vol. 41, # 9 p. 689 - 692
参考文献
Annali di Chimica (Rome, Italy), , vol. 49, p. 1649,1656, 1663
