5-[(4-氨基苯基)磺酰基氨基]-1,3,4-噻二唑-2-磺酰胺合成路线 （共 5 条）
反应条件
1: With hydrogenchloride in water 0.833333 h; HeatingReflux; 2: With ammonia in water
参考文献
Ahad, Ali Md.; Zuohe, Song; Du-Cuny, Lei; Moses, Sylvestor A.; Zhou, Li Li; Zhang, Shuxing; Powis, Garth; Meuillet, Emmanuelle J.; Mash, Eugene A.
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 6 p. 2046 - 2054
反应条件
1: HCl / 0.75 h / 100 °C View Scheme
参考文献
Supuran, Claudiu T.; Ilies, Marc A.; Scozzafava, Andrea
European Journal of Medicinal Chemistry, 1998 , vol. 33, # 9 p. 739 - 751
反应条件
sodium hydroxide; iodine; potassium iodide T=0 - 4°C;
参考文献
Supuran, Claudiu T; Briganti, Fabrizio; Tilli, Silvia; Chegwidden; Scozzafava, Andrea
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 3 p. 703 - 714
反应条件
sodium hydroxide; sodium hypochlorite T=25 - 30°C;
参考文献
Supuran, Claudiu T; Briganti, Fabrizio; Tilli, Silvia; Chegwidden; Scozzafava, Andrea
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 3 p. 703 - 714
反应条件
sodium hydroxide; sodium hypochlorite
T=25 - 30°C; thiocarbamylation;
参考文献
Scozzafava, Andrea; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 10 p. 1117 - 1120
