23-叠氮基-3,6,9,12,15,18,21-七氧杂二十三烷-1-醇合成路线 （共 10 条）
反应条件
1: With ozone in dichloromethane T=-78°C; 0.25 h; 2: With sodium tetrahydroborate in dichloromethane T=20°C; Inert atmosphere;
参考文献
Zona, Cristiano; D'Orazio, Giuseppe; La Ferla, Barbara
Synlett, 2013 , vol. 24, # 6 art. no. ST-2013-B0076-L, p. 709 - 712
反应条件
sodium azide in N,N-dimethyl-formamide T=65°C; 12 h;
参考文献
Goswami, Lalit N.; Houston, Zachary H.; Sarma, Saurav J.; Jalisatgi, Satish S.; Hawthorne, M. Frederick
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 7 p. 1116 - 1126
反应条件
1.1: pyridine 2.1: NaH / dimethylformamide / 0.5 h / 20 °C 2.2: dimethylformamide / 22 h / 20 °C 3.1: 0.51 g / p-TsOH / methanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 13 p. 4494 - 4503
反应条件
1: silver(l) oxide / dichloromethane / 24 h / 0 - 20 °C 2: sodium azide / N,N-dimethyl-formamide / 12 h / 65 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 7 p. 1116 - 1126
反应条件
1.1: 92 percent / Et3N / CH2Cl2 / 0.83 h / 0 - 20 °C 2.1: NaH / dimethylformamide / 0.5 h / 20 °C 2.2: dimethylformamide / 22 h / 20 °C 3.1: 0.51 g / p-TsOH / methanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 13 p. 4494 - 4503
反应条件
1.1: NaH / dimethylformamide / 0.5 h / 20 °C 1.2: dimethylformamide / 22 h / 20 °C 2.1: 0.51 g / p-TsOH / methanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 13 p. 4494 - 4503
反应条件
1.1: 94 percent / sodium azide / dimethylformamide / 2.5 h / 110 °C 2.1: 92 percent / Et3N / CH2Cl2 / 0.83 h / 0 - 20 °C 3.1: NaH / dimethylformamide / 0.5 h / 20 °C 3.2: dimethylformamide / 22 h / 20 °C 4.1: 0.51 g / p-TsOH / methanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 13 p. 4494 - 4503
反应条件
1.1: NaH / dimethylformamide / 0.5 h / 20 °C 1.2: dimethylformamide / 22 h / 20 °C 2.1: 0.51 g / p-TsOH / methanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 13 p. 4494 - 4503
反应条件
1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.33 h 1.2: 20 °C 2.1: ozone / dichloromethane / 0.25 h / -78 °C 2.2: 20 °C / |Inert atmosphere View Scheme
参考文献
Synlett, , vol. 24, # 6 art. no. ST-2013-B0076-L, p. 709 - 712
反应条件
1: With triphenylphosphine in tetrahydrofuran T=20°C; Staudinger reduction reaction; 20 h; 2: With water in tetrahydrofuran Further stages.;
参考文献
Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson
Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503
