1: With triphenylphosphine in tetrahydrofuran T=20°C; Staudinger reduction reaction; 20 h; 2: With water in tetrahydrofuran Further stages.;

1.1: pyridine 2.1: NaH / dimethylformamide / 0.5 h / 20 °C 2.2: dimethylformamide / 22 h / 20 °C 3.1: 0.51 g / p-TsOH / methanol 4.1: Ph3P / tetrahydrofuran / 20 h / 20 °C 4.2: 90 percent / H2O / tetrahydrofuran View Scheme

1.1: 92 percent / Et3N / CH2Cl2 / 0.83 h / 0 - 20 °C 2.1: NaH / dimethylformamide / 0.5 h / 20 °C 2.2: dimethylformamide / 22 h / 20 °C 3.1: 0.51 g / p-TsOH / methanol 4.1: Ph3P / tetrahydrofuran / 20 h / 20 °C 4.2: 90 percent / H2O / tetrahydrofuran View Scheme

1.1: NaH / dimethylformamide / 0.5 h / 20 °C 1.2: dimethylformamide / 22 h / 20 °C 2.1: 0.51 g / p-TsOH / methanol 3.1: Ph3P / tetrahydrofuran / 20 h / 20 °C 3.2: 90 percent / H2O / tetrahydrofuran View Scheme

1.1: 94 percent / sodium azide / dimethylformamide / 2.5 h / 110 °C 2.1: 92 percent / Et3N / CH2Cl2 / 0.83 h / 0 - 20 °C 3.1: NaH / dimethylformamide / 0.5 h / 20 °C 3.2: dimethylformamide / 22 h / 20 °C 4.1: 0.51 g / p-TsOH / methanol 5.1: Ph3P / tetrahydrofuran / 20 h / 20 °C 5.2: 90 percent / H2O / tetrahydrofuran View Scheme

1.1: NaH / dimethylformamide / 0.5 h / 20 °C 1.2: dimethylformamide / 22 h / 20 °C 2.1: 0.51 g / p-TsOH / methanol 3.1: Ph3P / tetrahydrofuran / 20 h / 20 °C 3.2: 90 percent / H2O / tetrahydrofuran View Scheme