4-(4-叔丁基苯基)-4-氧丁酸合成路线 （共 8 条）
反应条件
1: With AlCl3, aluminium chloride in anhydrous dichloroethane T=20°C; 1 h; Heating / reflux; 2: With hydrogenchloride in anhydrous dichloroethane; water T=20°C; 0.166667 h;
参考文献
LUPIN LIMITED
Patent: WO2004/26848 A1, 2004 ;
Location in patent: Page 34 ;
反应条件
1: FeCl3 2: aluminium chloride; carbon disulfide View Scheme
参考文献
Journal of the Chemical Society, , p. 144
反应条件
potassium hydroxide; hydrazine in ethylene glycol 8 h; Reflux;
参考文献
TOTAL PETROCHEMICALS RESEARCH FELUY; GOSUDARSTVENNOE UCHEBNO-NAUCHNOE UCHREZHDENIE KHIMICHESKY FAKULTET MOSKOVSKOGO GOSUDARSTVENNOGO UNIVERSITETA IM. M.V.LOMONOSOVA; VOSKOBOYNIKOV, Alexander, Z.; IZMER, Vyatcheslav, V.; KONONOVICH, Dmitry, S.; RAZAVI, Abbas
Patent: WO2010/76188 A1, 2010 ;
Location in patent: Page/Page column 13-15 ;
反应条件
hydrogenchloride; acetic acid; aluminium trichloride in dichloromethane; water; toluene
参考文献
Pennwalt Corporation
Patent: US4855462 A1, 1989 ;
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5716944 A1, 1998 ;
反应条件
conc. sulphuric acid in ethanol; water
参考文献
IMPERIAL CHEMICAL INDUSTRIES PLC
Patent: EP251466 A3, 1989 ;
反应条件
1: NH2NH2*H2O, KOH / ethane-1,2-diol / 3 h / Heating
2: KOH / ethane-1,2-diol / 12 h / Heating
3: PCl5 / benzene / 0.08 h / Heating
4: SnCl4 / benzene / 6 h / 0 °C
5: 31 percent / diethyl ether / 0.5 h / Heating
6: 80 percent / HCO2H
7: 61 percent / 10percent Pd/C / 0.75 h / 260 - 290 °C
View Scheme
参考文献
Jackson, Richard A.; Rhodes, Christopher J.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1993 , # 1 p. 53 - 57
