in diethyl ether; toluene 1.44M Et2O soln. of NeophMgCl (1.7-2.05 equiv.) dropwise with stirring added to toluene soln. of SnCl4 (1 equiv.) under N2 at room temp., heatedat reflux for 3 h, left at room temp. for 12 h; aq. satd. soln. NH4Cl added, organic layer separated, aq. layer extracted with Et2O, combined organic extracts dried over MgSO4, solvent removedunder vac., recrystd. from n-heptane; ratio of Nph3SnCl/Nph2SnCl2 was 6 0/40-24.5/75.5, NMR;

in not given according to J. Organomet. Chem. 2011, 696, 1547;

1: (2-methyl-2-phenylpropyl)MgCl With zinc(II) chloride in tetrahydrofuran 2: iodobenzene With dichloro bis(acetonitrile) palladium(II); diethyl bicyclo[2.2.1]hept-2,5-diene-2,3-dicarboxylate in tetrahydrofuran T=60°C; Negishi coupling reaction; 2 h; Inert atmosphere;

1: in diethyl ether T=-78 - 20°C; 2: With hydrogenchloride in diethyl ether; water; ethyl acetate

2-chloro-1,2-diphenyl-ethanone; zinc(II) chloride; ((S)-2,2′-bis(diphenylphosphino)-1,1′-binaphthyl)PdCl2*2THF T=20°C;

1: (2-methyl-2-phenylpropyl)MgCl With zinc(II) chloride in tetrahydrofuran T=20°C; 2: 1-tributylstannyl-2-phenylacetylene With bis(dibenzylideneacetone)-palladium(0) in dichloromethane Further stages.;

in diethyl ether byproducts: bineophyl; under Ar, Grignard reagent (prepared from Mg and neophylchloride), stirred under reflux (18 h), add. to GaCl3 soln. (30 min), stirred under reflux (18 h); vac. dest. at room temp., extraction from MgCl2, washed (pentane), vac. dest. at 120-210°C (160-210°C pure product), recrystn. (pentane, -20°C); elem. anal.;

in diethyl ether 1 h reflux;

in diethyl ether; benzene final reflux in benzene;

1: diethyl ether; benzene View Scheme