8-苄基-1-?-8-氮杂螺[4.5]-2-癸酮合成路线 (共 3 条)
反应条件
sodium tris(acetoxy)borohydride; triethylamine in dichloromethane 14 h;
参考文献
MERCK and CO., INC.
Patent: WO2004/58763 A1, 2004 ;
Location in patent: Page 34 ;
WO 2004/058763 A1
反应条件
phosphoric acid; phosphorus pentoxide T=145°C; 24 h;
参考文献
Wittekind,R.R.; Weissman,C.
Journal of Heterocyclic Chemistry, 1972 , vol. 9, p. 111 - 113
反应条件
potassium hydroxide; sodium ethanolate Yield given. Multistep reaction;
参考文献
Satyamurthy, Nagichettiar; Berlin, K. Darrell; Powell, Douglas R.; Helm, Dick van der
Phosphorus and Sulfur and the Related Elements, 1984 , vol. 19, p. 137 - 154