2-碘-1,1,1-三氟乙烷合成路线 （共 59 条）
反应条件
sodium hydride in pyridine T=20°C; 2 h; Product distribution / selectivity;
参考文献
Nanno, Tetsuo; Deguchi, Masaki
Patent: US2008/306308 A1, 2008 ;
Location in patent: Page/Page column 7-8 ;
反应条件
in dichloromethane T=20°C; 1 h; Inert atmosphere;
参考文献
Ochiai, Masahito; Nakano, Aiko; Yoshimura, Akira; Miyamoto, Kazunori; Hayashi, Satoko; Nakanishi, Waro
Chemical Communications, 2009 , # 8 p. 959 - 961
反应条件
potassium carbonate in DMF (N,N-dimethyl-formamide) T=150°C; 0.5 h; microwave;
参考文献
Merck and Co., Inc; Synaptic Pharmaceutical Corporation
Patent: US6376503 B1, 2002 ;
US 6376503 B1
反应条件
dihydrogen peroxide T=-15 - 20°C; 72 h;
参考文献
Journal of Fluorine Chemistry, , vol. 128, # 10 p. 1326 - 1334
反应条件
in tetrahydrofuran Co-complex was suspended in THF and CF3CH2I was added with stirring, allowed to stir for a few min at room temp., petroleum ether was added under N2; filtered, solvent was removed under vac., solid was dissolved in benzene and applied to silica gel-benzene-petroleum ether column, eluted, solvent was removed under vac.; elem. anal.;
参考文献
Schore, Neil E.; Ilenda, Casmir S.; White, Mary Ann; Bryndza, Henry E.; Matturro, Michael G.; Bergman, Robert G.
Journal of the American Chemical Society, 1984 , vol. 106, # 24 p. 7451 - 7461
反应条件
sodium dithionite; sodium hydrogencarbonate in dimethyl sulfoxide T=50°C; 4 h;
参考文献
Long, Zheng-Yu; Chen, Qing-Yun
Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8487 - 8490
反应条件
sodium dithionite; sodium hydrogencarbonate in water; acetonitrile T=60°C; 6 h; Yield given. Yields of byproduct given;
参考文献
Long, Zheng-Yu; Chen, Qing-Yun
Tetrahedron Letters, 1998 , vol. 39, # 46 p. 8487 - 8490
反应条件
cesium fluoride in diethylene glycol dimethyl ether T=70°C; 24 h;
参考文献
Murata, Junji; Tamura, Masanori; Sekiya, Akira
Journal of Fluorine Chemistry, 2002 , vol. 113, # 1 p. 97 - 100
反应条件
sodium hydride in N,N-dimethyl-formamide T=120 - 130°C; 67 h; sealed;
参考文献
Journal of Fluorine Chemistry, , vol. 40, p. 81 - 98
反应条件
in dimethyl sulfoxide T=25°C; Pt-Ag/Ag3 electrode; Equilibrium constant;
参考文献
Bordwell, F. G.; Wilson, Craig A.
Journal of the American Chemical Society, 1987 , vol. 109, # 18 p. 5470 - 5474
