9-羟基-4-甲氧基吖啶合成路线 （共 16 条）
参考文献
Nadaraj; Kalaivani; Selvi, S. Thamarai
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 8 p. 1958 - 1960
反应条件
anhydrous heptafluorobutyric acid Heating;
参考文献
Iwao, M.; Reed, J. N.; Snieckus, V.
Journal of the American Chemical Society, 1982 , vol. 104, # 20 p. 5531 - 5533
反应条件
1: 83 percent / copper; potassium carbonate / 3-methyl-butan-1-ol / Heating 2: 90 percent / polyphosphoric acid / 100 °C View Scheme
参考文献
Eur. J. Med. Chem., , vol. 39, # 2 p. 161 - 178
反应条件
1: 88 percent / K2CO3; Cu / pentan-1-ol 2: 50 percent / H2SO4 / 4 h / 100 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 124, # 42 p. 12453 - 12462
反应条件
1: 2.) oxygen / 1.) cyclohexane, THF, 2 h, 2.) -78 deg C, 30 min 2: 58 percent / heptafluorobutyric acid / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 104, # 20 p. 5531 - 5533
反应条件
in various solvent(s) 6 h; Heating;
参考文献
Hawkins, David G.; Meth-Cohn, Otto
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 2077 - 2087
反应条件
1: 1.) conc. HCl, sodium nitrite, 2.) sodium azide, sodium acetate / 1.) acetic acid, water, below 5 deg C 2: 87 percent / various solvent(s) / 3 h / Heating 3: 62 percent / various solvent(s) / 6 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2077 - 2087
反应条件
1: copper(l) iodide; potassium carbonate; L-proline / 3-methyl-1-butanol / 1 h / 140 °C / Microwave irradiation 2: trichlorophosphate / 2 h / Inert atmosphere; Reflux 3: hydrogenchloride / ethanol; water / 1 h / Reflux View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 54, p. 10 - 21
反应条件
1: copper(l) iodide; potassium carbonate; L-proline / 3-methyl-1-butanol / 1 h / 140 °C / Microwave irradiation 2: trichlorophosphate / 2 h / Inert atmosphere; Reflux 3: hydrogenchloride / ethanol; water / 1 h / Reflux View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 54, p. 10 - 21
反应条件
1: trichlorophosphate / 2 h / Inert atmosphere; Reflux 2: hydrogenchloride / ethanol; water / 1 h / Reflux View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 54, p. 10 - 21
