5-氧代吡咯烷-3-甲酸甲酯合成路线 （共 9 条）
反应条件
ammonium chloride; triethylamine in methanol T=20°C; Michael addition;
参考文献
Felluga, Fulvia; Pitacco, Giuliana; Prodan, Massimo; Pricl, Sabrina; Visintin, Marco; Valentin, Ennio
Tetrahedron Asymmetry, 2001 , vol. 12, # 23 p. 3241 - 3249
反应条件
1: 98 percent / water, tetrabutylammonium fluoride / dimethylformamide; tetrahydrofuran / 36 h / Ambient temperature 2: 68 percent / conc. HCl / methanol / 0.08 h / Ambient temperature 3: 94 percent / Et3N / methanol / 2 h / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 59, p. 2537 - 2546
反应条件
1: 68 percent / conc. HCl / methanol / 0.08 h / Ambient temperature 2: 94 percent / Et3N / methanol / 2 h / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 59, p. 2537 - 2546
参考文献
Organic Letters, , vol. 10, # 23 p. 5353 - 5356
反应条件
lithium borohydride in tetrahydrofuran T=20°C;
参考文献
Zischinsky, Gunther; Osterkamp, Frank; Vossmeyer, Doerte; Zahn, Grit; Scharn, Dirk; Zwintscher, Ariane; Stragies, Roland
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 380 - 382
反应条件
pig liver acetone powder in phosphate buffer T=20°C; pH=7.4; Product distribution; Further Variations:different conversion;
参考文献
Felluga, Fulvia; Pitacco, Giuliana; Prodan, Massimo; Pricl, Sabrina; Visintin, Marco; Valentin, Ennio
Tetrahedron Asymmetry, 2001 , vol. 12, # 23 p. 3241 - 3249
反应条件
Lawesson's reagent in tetrahydrofuran
T=20°C; 2 h;
参考文献
Stanetty, Peter; Turner, Martin; Mihovilovic, Marko D.
Molecules, 2005 , vol. 10, # 2 p. 367 - 375
参考文献
Hoechst Aktiengesellschaft
Patent: US4548936 A1, 1985 ;
反应条件
1: 99 percent / Lawesson's reagent / tetrahydrofuran / 2 h / 20 °C
2: 30 percent / triethylamine; DMAP / CH2Cl2 / 12 h / 20 °C
View Scheme
参考文献
Stanetty, Peter; Turner, Martin; Mihovilovic, Marko D.
Molecules, 2005 , vol. 10, # 2 p. 367 - 375
