(R)-(-)-2-氨基-1-丙醇合成路线 (共 32 条)
反应条件
phosphoric acid; hydrogen in water T=100°C; P=51714.8 Torr; 6 h; Product distribution; Further Variations:TemperaturesPressures;
参考文献
Organic Letters, , vol. 5, # 4 p. 527 - 530
反应条件
sodium hydroxide T=80°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 52, # 23 p. 5079 - 5082
反应条件
sodium hydroxide T=80°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 52, # 23 p. 5079 - 5082
反应条件
lithium aluminium tetrahydride
参考文献
Elz; Drager; Schunack
1987 , vol. 42, # 3 p. 348 - 354
反应条件
oxalic acid; palladium Hydrogenolyse;
参考文献
US2229187 , ;
US2243977 , ;
Helvetica Chimica Acta, , vol. 26, p. 929,936,937
反应条件
(S)-selective ω-transaminase from Ochrobactrum anthropi; L-threonine deaminase from Escherichia coli; pyridoxal 5'-phosphate T=37°C; pH=7.5; 30 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Green Chemistry, , vol. 14, # 8 p. 2137 - 2140
参考文献
Science (Washington, DC, United States), , vol. 82, p. 17
Chem. Zentralbl., , vol. 106, # II p. 2821
反应条件
1: hexadecanoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine in ethyl acetate T=20°C; 1 h; 2: (2R)-2-amino-1-propanol in ethyl acetate T=20°C; 12 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 4 p. 1520 - 1527
反应条件
T=120°C; 5 h; Inert atmosphere;
参考文献
WO2013/121449 A1, ;
Page/Page column 22-24 ;
反应条件
1: 3-phenyl-propionaldehyde With 1-hydroxy-pyrrolidine-2,5-dione; oxygen; [Co(O2CCH3)2]*4H2O in acetonitrile T=20°C; P=760.051 Torr; 24 h; Molecular sieve; 2: (2R)-2-amino-1-propanol in acetonitrile T=20°C; Molecular sieveInert atmosphere;
参考文献
Yao, Haoyi; Yamamoto, Kana
Chemistry - An Asian Journal, 2012 , vol. 7, # 7 p. 1542 - 1545