2-(2-碘-4,5-二甲氧基苯基)乙酸合成路线 （共 9 条）
反应条件
iodine cloride in acetic acid T=20°C; 1.5 h;
参考文献
Olivera, Roberto; SanMartin, Raul; Churruca, Fatima; Dominguez, Esther
Journal of Organic Chemistry, 2002 , vol. 67, # 21 p. 7215 - 7225
反应条件
1: 100 percent / thionyl chloride / 0 - 20 °C 2: dimethyl(3-(pyren-1-yl)propyl)stannane; AIBN / benzene / 1 h / Heating View Scheme
参考文献
Stien, Didier; Gastaldi, Stephane
Journal of Organic Chemistry, 2004 , vol. 69, # 13 p. 4464 - 4470
反应条件
potassium tert-butylate in ammonia 0.25 h; Irradiation;
参考文献
Heterocycles, , vol. 23, # 5 p. 1197 - 1203
反应条件
potassium tert-butylate in ammonia 0.25 h; Irradiation;
参考文献
Heterocycles, , vol. 23, # 5 p. 1197 - 1203
反应条件
potassium tert-butylate in ammonia 0.416667 h; Irradiation;
参考文献
Heterocycles, , vol. 23, # 5 p. 1197 - 1203
反应条件
Amberlyst Inert atmosphere;
参考文献
Cueva, Juan Pablo; Gallardo-Godoy, Alejandra; Juncosa, Jose I.; Vidi, Pierre A.; Lill, Markus A.; Watts, Val J.; Nichols, David E.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 15 p. 5508 - 5521
反应条件
1.1: 92 percent / SOCl2 / 20 °C 2.1: 96 percent / Et3N / [PdCl2(PPh3)2] / acetonitrile / 6 h / Heating 3.1: 100 percent / H2 / 10 percent Pd/C / ethanol / 2585.74 Torr 4.1: KO-tert-Bu / diethyl ether / 0.5 h 4.2: 62 percent / LiCl; HCl; H2O / dimethylsulfoxide / 5 h / 125 °C View Scheme
参考文献
Qandil, Amjad M.; Miller, David W.; Nichols, David E.
Synthesis, 1999 , # 12 p. 2033 - 2035
反应条件
dimethylsulfide borane complex in tetrahydrofuran
T=25°C; 12 h;
参考文献
Huang, Qinhua; Larock, Richard C.
Organic Letters, 2002 , vol. 4, # 15 p. 2505 - 2508
反应条件
potassium hydroxide; copper
参考文献
Sindelar; Kackac; Holubek; et al.
Collection of Czechoslovak Chemical Communications, 1976 , vol. 41, # 5 p. 1396 - 1415
